CHEBI:137020 - resolvin T4

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ChEBI Name resolvin T4
ChEBI ID CHEBI:137020
Definition A docosanoid that is (8E,10Z,14E,16Z,19Z)-docosapentaenoic acid carrying two hydroxy substituents at positions 7 and 13.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ChemicalBook:CB22589642, Selleckchem:tideglusib, ZINC000013985228
Download Molfile XML SDF
Formula C22H34O4
Net Charge 0
Average Mass 362.504
Monoisotopic Mass 362.24571
InChI InChI=1S/C22H34O4/c1-2-3-4-5-6-7-10-15-20(23)16-11-8-12-17-21(24)18-13-9-14-19-22(25)26/h3-4,6-8,10-12,15,17,20-21,23-24H,2,5,9,13-14,16,18-19H2,1H3,(H,25,26)/b4-3-,7-6-,11-8-,15-10+,17-12+
InChIKey BCWQNTXSYCKTHB-QIDYMIIRSA-N
SMILES CC/C=C\C\C=C/C=C/C(C\C=C/C=C/C(CCCCCC(=O)O)O)O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) See: PubMed
Homo Sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing resolvin T4 (CHEBI:137020) has role anti-inflammatory agent (CHEBI:67079)
resolvin T4 (CHEBI:137020) has role human xenobiotic metabolite (CHEBI:76967)
resolvin T4 (CHEBI:137020) has role mouse metabolite (CHEBI:75771)
resolvin T4 (CHEBI:137020) is a docosanoid (CHEBI:131863)
resolvin T4 (CHEBI:137020) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin T4 (CHEBI:137020) is a resolvin (CHEBI:132120)
resolvin T4 (CHEBI:137020) is conjugate acid of resolvin T4(1−) (CHEBI:134659)
Incoming resolvin T4(1−) (CHEBI:134659) is conjugate base of resolvin T4 (CHEBI:137020)
IUPAC Name
(8E,10Z,14E,16Z,19Z)-7,13-dihydroxydocosa-8,10,14,16,19-pentaenoic acid
Synonyms Sources
(8E,10Z,14E,16Z,19Z)-7,13-dihydroxydocosapentaenoic acid ChEBI
13-series resolvin 4 ChEBI
RvT4 ChEBI
Citations Waiting for Citations Types Sources
26236990 PubMed citation Europe PMC
27704804 PubMed citation Europe PMC
Last Modified
05 March 2018
General Comment
2017-05-11 The stereochemistry of the 13-hydroxy group is assumed but not yet formally proven; the stereochemistry at position 7 has not yet been determined.