CHEBI:137018 - resolvin T2

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ChEBI Name resolvin T2
ChEBI ID CHEBI:137018
Definition A docosanoid that is (8Z,10E,14E,16Z,19Z)-docosapentaenoic acid carrying three hydroxy substituents at positions 7, 12 and 13.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information ZINC000030729497
Download Molfile XML SDF
Formula C22H34O5
Net Charge 0
Average Mass 378.503
Monoisotopic Mass 378.24062
InChI InChI=1S/C22H34O5/c1-2-3-4-5-6-7-10-16-20(24)21(25)17-13-12-15-19(23)14-9-8-11-18-22(26)27/h3-4,6-7,10,12-13,15-17,19-21,23-25H,2,5,8-9,11,14,18H2,1H3,(H,26,27)/b4-3-,7-6-,15-12-,16-10+,17-13+
InChIKey XFIHWRRFJFILNC-FFAJSMOKSA-N
SMILES CC/C=C\C/C=C\C=C\C(C(/C=C/C=C\C(CCCCCC(O)=O)O)O)O
Metabolite of Species Details
Mus musculus (NCBI:txid10090) See: PubMed
Homo Sapiens (NCBI:txid9606) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
Application(s): anti-inflammatory agent
Any compound that has anti-inflammatory effects.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
(via resolvin )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing resolvin T2 (CHEBI:137018) has role anti-inflammatory agent (CHEBI:67079)
resolvin T2 (CHEBI:137018) has role human xenobiotic metabolite (CHEBI:76967)
resolvin T2 (CHEBI:137018) has role mouse metabolite (CHEBI:75771)
resolvin T2 (CHEBI:137018) is a docosanoid (CHEBI:131863)
resolvin T2 (CHEBI:137018) is a hydroxy polyunsaturated fatty acid (CHEBI:140345)
resolvin T2 (CHEBI:137018) is a resolvin (CHEBI:132120)
resolvin T2 (CHEBI:137018) is conjugate acid of resolvin T2(1−) (CHEBI:134657)
Incoming resolvin T2(1−) (CHEBI:134657) is conjugate base of resolvin T2 (CHEBI:137018)
IUPAC Name
(8Z,10E,14E,16Z,19Z)-7,12,13-trihydroxydocosa-8,10,14,16,19-pentaenoic acid
Synonyms Sources
(8Z,10E,14E,16Z,19Z)-7,12,13-trihydroxydocosapentaenoic acid ChEBI
13-series resolvin 2 ChEBI
RvT2 ChEBI
Citations Types Sources
26236990 PubMed citation Europe PMC
27704804 PubMed citation Europe PMC
Last Modified
05 March 2018
General Comment
2017-05-11 The stereochemistry of the 13-hydroxy group is assumed but not yet formally proven; the stereochemistry at positions 7 and 12 has not yet been determined.