taurolidine (CHEBI:135173)

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ChEBI Name	taurolidine

ChEBI ID	CHEBI:135173

Definition	A member of the class of thiadiazinanes that is 1,2,4-thiadiazinane 1,1-dioxide substituted by a (1,1-dioxido-1,2,4-thiadiazinan-4-yl)methyl group at position 4. It is a broad-spectrum antiseptic used as lock therapy solution in patients with long term central venous catheters for the prevention of catheter related bloodstream infections.

Stars	This entity has been manually annotated by the ChEBI Team.

Supplier Information	ChemicalBook:CB7845341, eMolecules:2728761, ZINC000019322537

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Formula

C7H16N4O4S2

Net Charge

Average Mass

284.350

Monoisotopic Mass

284.06130

InChI

InChI=1S/C7H16N4O4S2/c12-16(13)3-1-10(5-8-16)7-11-2-4-17(14,15)9-6-11/h8-9H,1-7H2

InChIKey

AJKIRUJIDFJUKJ-UHFFFAOYSA-N

SMILES

O=S1(=O)CCN(CN2CCS(=O)(=O)NC2)CN1

Roles Classification
Biological Role(s):	antibacterial agent A substance (or active part thereof) that kills or slows the growth of bacteria. antifungal agent An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.

Application(s):	anti-inflammatory agent Any compound that has anti-inflammatory effects. antiseptic drug A substance used locally on humans and other animals to destroy harmful microorganisms or to inhibit their activity (cf. disinfectants, which destroy microorganisms found on non-living objects, and antibiotics, which can be transported through the lymphatic system to destroy bacteria within the body). antineoplastic agent A substance that inhibits or prevents the proliferation of neoplasms.

ChEBI Ontology
Outgoing	taurolidine (CHEBI:135173) has role anti-inflammatory agent (CHEBI:67079) taurolidine (CHEBI:135173) has role antibacterial agent (CHEBI:33282) taurolidine (CHEBI:135173) has role antifungal agent (CHEBI:35718) taurolidine (CHEBI:135173) has role antineoplastic agent (CHEBI:35610) taurolidine (CHEBI:135173) has role antiseptic drug (CHEBI:48218) taurolidine (CHEBI:135173) is a sulfone (CHEBI:35850) taurolidine (CHEBI:135173) is a thiadiazinane (CHEBI:38781)

Incoming	Defencath (CHEBI:230518) has part taurolidine (CHEBI:135173)

IUPAC Name

4,4'-methanediylbis(1,2,4-thiadiazinane) 1,1,1',1'-tetraoxide

Synonyms	Sources
4,4'-methylenebis(1,2,4-thiadiazinane)-1,1,1',1'-tetraoxide	ChEBI
4,4'-methylenebis(perhydro-1,2,4-thiadiazin 1,1-dioxide)	ChEBI
4,4'-methylenedi(1λ⁶,2,4-thiadiazinane-1,1-dione)	IUPAC
taurolin	DrugCentral
tauroline	DrugCentral
W-3100M	DrugBank

Registry Number	Type	Source
19388-87-5	CAS Registry Number	KEGG DRUG

Citations

Last Modified

19 April 2024