CHEBI:131186 - IP3 receptor antagonist

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ChEBI Name IP3 receptor antagonist
ChEBI ID CHEBI:131186
Definition An antagonist that binds to and deactivates IP3 receptors.
Stars This entity has been manually annotated by the ChEBI Team.
Wikipedia License
Inositol trisphosphate receptor (InsP3R) is a membrane glycoprotein complex acting as a Ca2+ channel activated by inositol trisphosphate (InsP3). InsP3R is very diverse among organisms, and is necessary for the control of cellular and physiological processes including cell division, cell proliferation, apoptosis, fertilization, development, behavior, learning and memory. Inositol triphosphate receptor represents a dominant second messenger leading to the release of Ca2+ from intracellular store sites. There is strong evidence suggesting that the InsP3R plays an important role in the conversion of external stimuli to intracellular Ca2+ signals characterized by complex patterns relative to both space and time, such as Ca2+ waves and oscillations.
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ChEBI Ontology
Outgoing IP3 receptor antagonist (CHEBI:131186) is a antagonist (CHEBI:48706)
Incoming 2-aminoethoxydiphenylborane (CHEBI:131184) has role IP3 receptor antagonist (CHEBI:131186)
xestospongin C (CHEBI:131784) has role IP3 receptor antagonist (CHEBI:131186)
Synonyms Sources
D-myo-inositol 1,4,5-trisphosphate receptor antagonist ChEBI
D-myo-inositol 1,4,5-trisphosphate receptor antagonists ChEBI
inositol trisphosphate receptor antagonist ChEBI
inositol trisphosphate receptor antagonists ChEBI
InsP3R antagonist ChEBI
InsP3R antagonists ChEBI
IP3 antagonist ChEBI
IP3 antagonists ChEBI
IP3 receptor antagonists ChEBI
Manual Xref Database
Inositol_trisphosphate_receptor Wikipedia
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Last Modified
08 December 2022