CHEBI:10033 - warfarin

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ChEBI Name warfarin
ChEBI ID CHEBI:10033
Definition A racemate comprising equal amounts of (R)- and (S)-warfarin. Extensively used as both an anticoagulant drug and as a pesticide against rats and mice.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H16O4
Net Charge 0
Average Mass 308.333
Monoisotopic Mass 308.10486
Roles Classification
Biological Role(s): EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor
An EC 1.6.5.* (oxidoreductase acting on NADH or NADPH with a quinone or similar as acceptor) inhibitor that interferes with the action of NAD(P)H dehydrogenase (quinone), EC 1.6.5.2.
vitamin K antagonist
A class of anticoagulants which act by inhibiting the action of vitamin K.
Application(s): anticoagulant
An agent that prevents blood clotting.
rodenticide
A substance used to destroy rodent pests.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing warfarin (CHEBI:10033) has part (R)-warfarin (CHEBI:87737)
warfarin (CHEBI:10033) has part (S)-warfarin (CHEBI:87738)
warfarin (CHEBI:10033) has role anticoagulant (CHEBI:50249)
warfarin (CHEBI:10033) has role EC 1.6.5.2 [NAD(P)H dehydrogenase (quinone)] inhibitor (CHEBI:50390)
warfarin (CHEBI:10033) has role rodenticide (CHEBI:33288)
warfarin (CHEBI:10033) has role vitamin K antagonist (CHEBI:55347)
warfarin (CHEBI:10033) is a racemate (CHEBI:60911)
warfarin (CHEBI:10033) is conjugate acid of warfarin(1−) (CHEBI:50393)
Incoming warfarin(1−) (CHEBI:50393) is conjugate base of warfarin (CHEBI:10033)
IUPAC Name
rac-4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one
INNs Sources
warfarin WHO MedNet
warfarina WHO MedNet
warfarine WHO MedNet
warfarinum WHO MedNet
Synonyms Sources
(±)-warfarin NIST Chemistry WebBook
(RS)-warfarin NIST Chemistry WebBook
4-hydroxy-3-[(1RS)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-2-one IUPAC
4-hydroxy-3-[(1RS)-3-oxo-1-phenylbutyl]-2H-chromen-2-one IUPAC
4-hydroxy-3-[(1RS)-3-oxo-1-phenylbutyl]coumarin PPDB
Coumafene ChemIDplus
DL-3-(α-acetonylbenzyl)-4-hydroxycoumarin NIST Chemistry WebBook
DL-warfarin ChEBI
rac-1-(4'-hydroxy-3'-coumarinyl)-1-phenyl-3-butanone ChemIDplus
rac-3-(1'-phenyl-2'-acetylethyl)-4-hydroxycoumarin ChemIDplus
rac-3-(acetonylbenzyl)-4-hydroxycoumarin NIST Chemistry WebBook
rac-3-(α-acetonylbenzyl)-4-hydroxycoumarin NIST Chemistry WebBook
rac-3-(α-phenyl-β-acetylethyl)-4-hydroxycoumarin ChemIDplus
rac-4-hydroxy-3-(3-oxo-1-phenylbutyl)coumarin ChEBI
rac-warfarin ChEBI
racemic warfarin ChEBI
Zoocoumarin ChemIDplus
Brand Names Sources
Brumolin ChEBI
Kumadu ChEBI
Kumatox ChEBI
Ratron ChEBI
Rodafarin ChEBI
Warf 10 DrugBank
Manual Xrefs Databases
681 PPDB
C01541 KEGG COMPOUND
D08682 KEGG DRUG
DB00682 DrugBank
FDB022750 FooDB
HMDB0001935 HMDB
LSM-1405 LINCS
US2427578 Patent
US2765321 Patent
US2777859 Patent
US3239529 Patent
warfarin Alan Wood's Pesticides
Warfarin Wikipedia
View more database links
Registry Numbers Types Sources
1293536 Reaxys Registry Number Reaxys
81-81-2 CAS Registry Number KEGG COMPOUND
81-81-2 CAS Registry Number NIST Chemistry WebBook
81-81-2 CAS Registry Number ChemIDplus
Citations Types Sources
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Last Modified
07 November 2023