Ligand 4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy'-3',4',6'-tri-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
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Basic Ligand Information
Molecular Structure
C22H27N5O10S
4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy'-3',4',6'-tri-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole
OQSUEVFKDJXJHM-ZGJYDULXSA-N
Roles as Enzyme Ligand
Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
Ki Value (3 results)
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0.000101
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isozyme CA IX, in 10 mM HEPES (pH 7.5), 0.1 M NaClO4, at 20°C
0.00044
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isozyme CA II, in 10 mM HEPES (pH 7.5), 0.1 M NaClO4, at 20°C
0.005
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isozyme CA I, in 10 mM HEPES (pH 7.5), 0.1 M NaClO4, at 20°C
References & Links
Literature References (1)
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Inhibition of carbonic anhydrases with glycosyltriazole benzene sulfonamides
2008
Wilkinson, B.L.; Innocenti, A.; Vullo, D.; Supuran, C.T.; Poulsen, S.A.
J. Med. Chem.
51
1945-1953
Links to other databases for 4-[4-(aminosulfonyl)phenyl]-1-(2'-acetamido-2'-deoxy'-3',4',6'-tri-O-acetyl-beta-D-glucopyranosyl)-1H-1,2,3-triazole