<?xml version="1.0"?>


<!DOCTYPE rdf:RDF [
    <!ENTITY owl "http://www.w3.org/2002/07/owl#" >
    <!ENTITY dc "http://purl.org/dc/elements/1.1/" >
    <!ENTITY xsd "http://www.w3.org/2001/XMLSchema#" >
    <!ENTITY ru-meta "http://purl.org/imbi/ru-meta.owl#" >
    <!ENTITY skos "http://www.w3.org/2004/02/skos/core#" >
    <!ENTITY rdfs "http://www.w3.org/2000/01/rdf-schema#" >
    <!ENTITY rdf "http://www.w3.org/1999/02/22-rdf-syntax-ns#" >
]>


<rdf:RDF xmlns="http://purl.org/biotop/biotop.owl#"
     xml:base="http://purl.org/biotop/biotop.owl"
     xmlns:dc="http://purl.org/dc/elements/1.1/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:ru-meta="http://purl.org/imbi/ru-meta.owl#"
     xmlns:skos="http://www.w3.org/2004/02/skos/core#">
    <owl:Ontology rdf:about="http://purl.org/biotop/biotop.owl">
        <dc:creator>Stefan Schulz, Martin Boeker, Elena Beisswanger, Holger Stenzhorn, Djamila Raufie, Daniel Schober, Udo Hahn</dc:creator>
        <dc:rights>http://creativecommons.org/licenses/by/3.0</dc:rights>
        <dc:identifier>20120129</dc:identifier>
        <dc:subject>An experimental top level ontology for biology and medicine.</dc:subject>
        <dc:format>application/rdf+xml</dc:format>
        <dc:identifier>http://purl.org/biotop/biotop.owl</dc:identifier>
        <dc:description>Upper-Level ontology for Biology and Medicine. Compatible with BFO, DOLCE, and the UMLS Semantic Network (mapping files available)</dc:description>
        <dc:title>BioTop</dc:title>
        <dc:subject>Biology, Medicine</dc:subject>
        <dc:publisher>Institute of Medical Biometry and Medical Informatics, University Medical Center Freiburg, Stefan-Meier-Strasse 26, 79104 Freiburg, Germany

Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Auenbruggerplatz 2/V , 8036 Graz (Austria)</dc:publisher>
        <dc:description>BioTop Website:
http://purl.org/biotop


See related articles at:

http://www.google.com/search?q=Schulz+BioTop+site:www.ncbi.nlm.nih.gov/pmc/articles+ontology+OR+ontologies</dc:description>
        <owl:versionInfo>Last modification
Apr 24, 2012 by Stefan Schulz</owl:versionInfo>
        <owl:imports rdf:resource="http://purl.org/biotop/btl2.owl"/>
    </owl:Ontology>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.org/dc/elements/1.1/creator -->

    <owl:AnnotationProperty rdf:about="&dc;creator"/>
    


    <!-- http://purl.org/dc/elements/1.1/description -->

    <owl:AnnotationProperty rdf:about="&dc;description"/>
    


    <!-- http://purl.org/dc/elements/1.1/format -->

    <owl:AnnotationProperty rdf:about="&dc;format"/>
    


    <!-- http://purl.org/dc/elements/1.1/identifier -->

    <owl:AnnotationProperty rdf:about="&dc;identifier"/>
    


    <!-- http://purl.org/dc/elements/1.1/publisher -->

    <owl:AnnotationProperty rdf:about="&dc;publisher"/>
    


    <!-- http://purl.org/dc/elements/1.1/rights -->

    <owl:AnnotationProperty rdf:about="&dc;rights"/>
    


    <!-- http://purl.org/dc/elements/1.1/source -->

    <owl:AnnotationProperty rdf:about="&dc;source"/>
    


    <!-- http://purl.org/dc/elements/1.1/subject -->

    <owl:AnnotationProperty rdf:about="&dc;subject"/>
    


    <!-- http://purl.org/dc/elements/1.1/title -->

    <owl:AnnotationProperty rdf:about="&dc;title"/>
    


    <!-- http://purl.org/imbi/ru-meta.owl#definition -->

    <owl:AnnotationProperty rdf:about="&ru-meta;definition"/>
    


    <!-- http://purl.org/imbi/ru-meta.owl#synonym -->

    <owl:AnnotationProperty rdf:about="&ru-meta;synonym"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#comment -->

    <owl:AnnotationProperty rdf:about="&rdfs;comment"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#label -->

    <owl:AnnotationProperty rdf:about="&rdfs;label"/>
    


    <!-- http://www.w3.org/2000/01/rdf-schema#seeAlso -->

    <owl:AnnotationProperty rdf:about="&rdfs;seeAlso"/>
    


    <!-- http://www.w3.org/2002/07/owl#priorVersion -->

    <owl:AnnotationProperty rdf:about="&owl;priorVersion"/>
    


    <!-- http://www.w3.org/2002/07/owl#versionInfo -->

    <owl:AnnotationProperty rdf:about="&owl;versionInfo"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.org/biotop/biotop.owl#attachedTo -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#attachedTo">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>attached to</rdfs:label>
        <ru-meta:definition>Contiguous with a clear bona fide boundary between the connected parts.
Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#contiguousWith"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#branchOf -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#branchOf">
        <rdfs:label>branch of</rdfs:label>
        <ru-meta:definition>A is a branch of B if it is contiguous with B and if some flow of matter or energy of information flows form B to A.
Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#attachedTo"/>
        <owl:inverseOf rdf:resource="http://purl.org/biotop/biotop.owl#hasBranch"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#contiguousWith -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#contiguousWith">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>contiguous with</rdfs:label>
        <ru-meta:definition>ContiguousWith describes the connection between two material objects that abut and can transmit forces.

 </ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#physicallyAdjacentTo"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#continuousWith -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#continuousWith">
        <rdfs:label>continuous with</rdfs:label>
        <ru-meta:definition>Contiguous with a clear bona fide boundary between the connected parts.
Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118 </ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#contiguousWith"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#derivedInto -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#derivedInto">
        <rdf:type rdf:resource="&owl;TransitiveProperty"/>
        <rdfs:label>derived into</rdfs:label>
        <ru-meta:definition>DerivesFrom (inverse: derivedInto) holds between  distinct material objects  when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier object is included into the later. 

There is some instant of time t such that the first object exists only prior to and the second one  only subsequent to t. 

These relations are borrowed from the OBO Relation Ontology

Example:
&quot;Three simple kinds of instance-level derivation can then be distinguished (Figure 3): first, the succession of one single continuant by another single continuant across a temporal threshold (for example, this blastocyst derives from this zygote); second, the fusion of two or more continuants into one continuant (for example, this zygote derives from this sperm and from this ovum); and third, the fission of an earlier single continuant to create a plurality of later continuants (for example, these promyelocytes derive from this myeoloblast). &quot; from http://genomebiology.com/2005/6/5/R46</ru-meta:definition>
        <owl:inverseOf rdf:resource="http://purl.org/biotop/biotop.owl#derivesFrom"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#hasOrigin"/>
        <rdfs:domain rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
        <rdfs:range rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#derivesFrom -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#derivesFrom">
        <rdf:type rdf:resource="&owl;TransitiveProperty"/>
        <rdfs:label>derives from</rdfs:label>
        <ru-meta:definition>DerivesFrom (inverse: derivedInto) holds between  distinct material objects  when one succeeds the other across a temporal divide in such a way that at least a biologically significant portion of the matter of the earlier object is included into the later. 

There is some instant of time t such that the first object exists only prior to and the second one  only subsequent to t. 

These relations are borrowed from the OBO Relation Ontology

Example:
&quot;Three simple kinds of instance-level derivation can then be distinguished (Figure 3): first, the succession of one single continuant by another single continuant across a temporal threshold (for example, this blastocyst derives from this zygote); second, the fusion of two or more continuants into one continuant (for example, this zygote derives from this sperm and from this ovum); and third, the fission of an earlier single continuant to create a plurality of later continuants (for example, these promyelocytes derive from this myeoloblast). &quot; from http://genomebiology.com/2005/6/5/R46</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
        <rdfs:range rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
        <rdfs:domain rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#encodes -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#encodes">
        <rdfs:label>encodes</rdfs:label>
        <ru-meta:definition>EncodedBy (inverse: encodes) relates entities with symbols, which are information entities. In contrast to denotation, encoding entails that the makeup of the encoded entity is determined by the code. There is a dependence of the former on the latter. Note that the association of human-made codes with entities (e.g. for coding and classification systems like ICD-10) is nothing more than denotation and is therefore not in the scope of the encodedBy (encodes) relation.

Example: A material gene sequence is related to a sequence of nucleotide symbols (like ACCGATTGA) </ru-meta:definition>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#hasBranch -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#hasBranch">
        <rdfs:label>has branch</rdfs:label>
        <ru-meta:definition>B hasBranch A if it is contiguous with B and if some flow of matter or energy of information flows form B to A.
Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#attachedTo"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#hasDuration -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#hasDuration">
        <rdfs:label>has duration</rdfs:label>
        <ru-meta:definition>hasDuration relates a process with the time interval it covers.</ru-meta:definition>
        <rdfs:domain rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
        <rdfs:range rdf:resource="http://purl.org/biotop/btl2.owl#TimeInterval"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#hasOrigin -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#hasOrigin">
        <rdfs:label>has origin</rdfs:label>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#hasPointInTime -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#hasPointInTime">
        <rdfs:label>has point in time</rdfs:label>
        <ru-meta:definition>hasPointInTome relates a processual entity with some point in the interval it occupies. 
If there is no temporal extension (process boundary) it relates it to the time it occurs. </ru-meta:definition>
        <rdfs:range rdf:resource="http://purl.org/biotop/btl2.owl#PointInTime"/>
        <rdfs:domain rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#hasProperPhysicalPart -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart">
        <rdf:type rdf:resource="&owl;TransitiveProperty"/>
        <rdfs:label>has proper physical part</rdfs:label>
        <ru-meta:definition>hasProperPhysicalPart (inverse: properPhysicalPartOf) obtains between physical objects. The distinction between parthood and locatedness is complex and does not obey strict criteria. 
This relation is irreflexive, i.e. a physical object cannot have itself as a physical proper part.

Note that for abstract entities like information artefacts there is a separate relation pair &quot;abstractPartOf&quot; and &quot;hasAbstractPart&quot;

For processes there are the relations &quot;hasProcessualPart&quot; and &quot;processualPartOf&quot;

Examples: my thumb is a proper physical part of my hand, this keyboard is a proper physical part of my computer.</ru-meta:definition>
        <owl:inverseOf rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/btl2.owl#hasPart"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#isCooccurringWith -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#isCooccurringWith">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>cooccurring with</rdfs:label>
        <ru-meta:definition>The relation coocurring with relates two processes if their temporal extensions overlap.</ru-meta:definition>
        <rdfs:range rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
        <rdfs:domain rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#isEncodedBy -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#isEncodedBy">
        <rdfs:label>encodedBy</rdfs:label>
        <ru-meta:definition>EncodedBy (inverse: encodes) relates entities with symbols, which are information entities. In contrast to denotation, encoding entails that the makeup of the encoded entity is determined by the code. There is a dependence of the former on the latter. Note that the association of human-made codes with entities (e.g. for coding and classification systems like ICD-10) is nothing more than denotation and is therefore not in the scope of the encodedBy (encodes) relation.

Example: A material gene sequence is related to a sequence of nucleotide symbols (like ACCGATTGA) </ru-meta:definition>
        <owl:inverseOf rdf:resource="http://purl.org/biotop/biotop.owl#encodes"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>physically connected to</rdfs:label>
        <ru-meta:definition>physicallyConnectedTo (a symmetric relation) relates two spatially relevant entities (material entities or spaces) which overlap at least one point in space. 

Example: France is connected to Germany, my optic nerve is connected to my eyeball.</ru-meta:definition>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#isPhysicallyContainedIn -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#isPhysicallyContainedIn">
        <rdfs:label>physically contained in</rdfs:label>
        <ru-meta:definition>Containment is location without parthood. E.g. Food is contained in the stomach. 

Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118</ru-meta:definition>
        <owl:inverseOf rdf:resource="http://purl.org/biotop/biotop.owl#physicallyContains"/>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/btl2.owl#isIncludedIn"/>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#isPhysicallyDisconnectedFrom -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#isPhysicallyDisconnectedFrom">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>physically disconnected from</rdfs:label>
        <ru-meta:definition>No sharing of parts and no sharing of boundaries. 

Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118</ru-meta:definition>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#originatesFrom -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#originatesFrom">
        <rdfs:label>originates from</rdfs:label>
        <ru-meta:definition>originatesFrom relates two material objects one of which originates from the other in a very broad sense. 

It includes derivation (in the OBO RO sense), actual actual parts (provided they were always parts), as well as original (historical) parts.

Examples: see Subrelations</ru-meta:definition>
        <rdfs:range rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
        <rdfs:domain rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#physicallyAdjacentTo -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#physicallyAdjacentTo">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>physically adjacent to</rdfs:label>
        <ru-meta:definition>physicalAdjacentTo relates two physical objects that abut without physical overlap. 

Examples: see subrelations</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo"/>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#physicallyContains -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#physicallyContains">
        <rdfs:label>physically contains</rdfs:label>
        <ru-meta:definition>Containment is location without parthood. E.g. Food is contained in the stomach. 

Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118  </ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/btl2.owl#includes"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#physicallyInterconnects -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#physicallyInterconnects">
        <rdfs:label>physically interconnects</rdfs:label>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo"/>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#physicallySurroundedBy -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#physicallySurroundedBy">
        <rdfs:label>physically surrounded by</rdfs:label>
        <ru-meta:definition>Partly or completely covering from outside (establishing boundaries, enclosing, confining, enclosing, circumscribing)
</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo"/>
        <owl:inverseOf rdf:resource="http://purl.org/biotop/biotop.owl#physicallySurrounds"/>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#physicallySurrounds -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#physicallySurrounds">
        <rdfs:label>physically surrounds</rdfs:label>
        <ru-meta:definition>Partly or completely covering from outside (establishing boundaries, enclosing, confining, enclosing, circumscribing)
</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#physicallyTraverses -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#physicallyTraverses">
        <rdfs:label>physically traverses</rdfs:label>
        <ru-meta:definition>crossing over and crossing through</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#isPhysicallyConnectedTo"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#properPhysicalPartOf -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#properPhysicalPartOf">
        <rdf:type rdf:resource="&owl;TransitiveProperty"/>
        <rdfs:label>proper physical part of</rdfs:label>
        <ru-meta:definition>hasProperPhysicalPart (inverse: properPhysicalPartOf) obtains between physical objects. The distinction between parthood and locatedness is complex and does not obey strict criteria. 
This relation is irreflexive, i.e. a physical object cannot have itself as a physical proper part.

Note that for abstract entities like information artefacts there is a separate relation pair &quot;abstractPartOf&quot; and &quot;hasAbstractPart&quot;

For processes there are the relations &quot;hasProcessualPart&quot; and &quot;processualPartOf&quot;

Examples: my thumb is a proper physical part of my hand, this keyboard is a proper physical part of my computer.</ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/btl2.owl#isPartOf"/>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
    </owl:ObjectProperty>
    


    <!-- http://purl.org/biotop/biotop.owl#touches -->

    <owl:ObjectProperty rdf:about="http://purl.org/biotop/biotop.owl#touches">
        <rdf:type rdf:resource="&owl;SymmetricProperty"/>
        <rdfs:label>touches</rdfs:label>
        <ru-meta:definition>Abutting without mechanical connection.
Schulz S, Hahn U. Towards the ontological foundations of symbolic biological theories.
Artif Intell Med. 2007 Mar;39(3):237-50. PMID: 17321118 </ru-meta:definition>
        <rdfs:subPropertyOf rdf:resource="http://purl.org/biotop/biotop.owl#physicallyAdjacentTo"/>
        <rdfs:domain>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:domain>
        <rdfs:range>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:range>
    </owl:ObjectProperty>
    


    <!-- http://www.w3.org/2002/07/owl#topObjectProperty -->

    <owl:ObjectProperty rdf:about="&owl;topObjectProperty"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Data properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://www.w3.org/2002/07/owl#topDataProperty -->

    <owl:DatatypeProperty rdf:about="&owl;topDataProperty"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.org/biotop/biotop.owl#AcquiredAbnormalStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AcquiredAbnormalStructure">
        <rdfs:label>acquired abnormal structure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PathologicalStructure"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#CongenitalAbnormalStructure"/>
        <ru-meta:definition>biological structure that deviates from what is considered normal and that evolved during lifetime</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AcquiredPathologicalCondition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AcquiredPathologicalCondition">
        <rdfs:label>acquired pathological condition</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PathologicalValueRegion"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#CongenitalPathologicalCondition"/>
        <ru-meta:definition>Ill-formed state of a biological entity,acquired after birth [steschu 20071010]</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AcquiredPathologicalStaticProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AcquiredPathologicalStaticProcessualEntity">
        <rdfs:label>acquired pathological static processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#PathologicalStaticProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AcquiredPathologicalCondition"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:priorVersion>acquired pathological state</owl:priorVersion>
        <ru-meta:definition>pathological state acquired during lifetime</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ActionOnBiologicalSystem -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ActionOnBiologicalSystem">
        <rdfs:label>action on biological system</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasPatient"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>an action which externally acts upon a biological system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AdultOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AdultOrganism">
        <rdfs:label>adult organism</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#DevelopmentalQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AdultValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismByDevelopmentalStagePartition"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#EmbryonicOrganism"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#JuvenileOrganism"/>
        <ru-meta:definition>organism in reproductive phase</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AdultValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AdultValueRegion">
        <rdfs:label>adult value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion"/>
        <rdfs:comment>&quot;adult&quot; as the value of a developmental stage. E.g. a 4 year old dog has a quality which has its value located in &quot;adult value region&quot;.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Affecting -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Affecting">
        <rdfs:label>affecting</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <ru-meta:definition>Producing a direct effect on</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AgeQuality -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AgeQuality">
        <rdfs:label>age quality</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ObjectQuality"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:allValuesFrom>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:allValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>the quality of having a livespan</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Alga -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Alga">
        <rdfs:label>alga</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AlphaParticle -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AlphaParticle">
        <rdfs:label>alpha particle</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Atom"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Class>
                        <owl:complementOf>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Electron"/>
                            </owl:Restriction>
                        </owl:complementOf>
                    </owl:Class>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Neutron"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>Positively charged particles composed of two protons and two neutrons, i.e. equivalent to Helium nuclei </ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AminoAcidMoleculeOrResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidMoleculeOrResidue">
        <rdfs:label>amino acid molecule or residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#AminoAcidOrPeptideMoleculeOrStructure"/>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Monomer"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
        <rdfs:comment>In chemistry, an amino acid is any molecule that contains both amine and carboxyl functional groups. However, in biochemistry, this more general term is frequently used to refer to alpha amino acids (amino acids in which the amino and carboxylate functionalities are attached to the same carbon, called ?–carbon). Amino Acids have at least one amino and one carboxy group. Those having two carboxy groups have only one amino group and vice versa.</rdfs:comment>
        <ru-meta:definition>Amino Acids molecules or residues (residues as in peptide bonds)</ru-meta:definition>
        <rdfs:comment>(QCR) ro:hasPart some CarbonHydrogenSubstructure and ((hasComponent myx 2 CarboxyGroup) and (hasComponent min 1 CarboxyGroup) and (hasComponent exactly 1 AminoGroup)) or ((hasComponent max 2 AminoGroup) and (hasComponent min 1 AminoGroup) and (hasComponent exactly 1 CarboxyGroup))</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AminoAcidOrPeptideMoleculeOrStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidOrPeptideMoleculeOrStructure">
        <rdfs:label>amino acid or peptide molecule or structure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition"/>
        <ru-meta:definition>amino acids as monomers and polymers</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AminoAcidSequence -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidSequence">
        <rdfs:label>amino acid sequence</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AminoAcidMoleculeOrResidue"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AminoAcidMoleculeOrResidue"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
        <ru-meta:definition>Chain of amino acids, joined by peptide bonds. Folded or unfolded.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AminoAcidSequenceInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidSequenceInformation">
        <rdfs:label>amino acid sequence information</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SequenceInformation"/>
        <ru-meta:definition>The information that describes the make-up of a (physical) amino acid sequence.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AmountOfBodySubstance -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AmountOfBodySubstance">
        <rdfs:label>amount of body substance</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#CompoundOfCollectiveMaterialEntities"/>
        <ru-meta:definition>collection with molecules or atoms as granular parts (but which may have also bigger granular parts) that is produced by a biological system (e.g. blood, urine, ivory)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Amphibian -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Amphibian">
        <rdfs:label>amphibian</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Analyzing -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Analyzing">
        <rdfs:label>analyzing</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HumanAction"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AnimalCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AnimalCell">
        <rdfs:label>animal cell</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Cell"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#BacterialCell"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#PlantCell"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AnimalExcludingHuman -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AnimalExcludingHuman">
        <rdfs:label>animal excluding human</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman"/>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AnimalIncludingHuman -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman">
        <rdfs:label>animal including human</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Multicellular organisms of the kingdom Animalia</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AnimalLanguage -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AnimalLanguage">
        <rdfs:label>animal language</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LanguagePartition"/>
        <ru-meta:definition>language used in communication between animals</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AnimalPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AnimalPopulation">
        <rdfs:label>animal population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#AntibioticRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#AntibioticRole">
        <rdfs:label>antibiotic role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#DrugRole"/>
        <ru-meta:definition>the role a chemical plays if used to combat a bacterial infection</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ArchaebacterialCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ArchaebacterialCell">
        <rdfs:label>archaebacterial cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Prokaryote"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomArchaeaValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:synonym>Archaebacterium</ru-meta:synonym>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ArtefactRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ArtefactRole">
        <rdfs:label>artefact role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <ru-meta:definition>The role an entity plays when it has been artificially produced. [steschu 20071010]</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Arthropod -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Arthropod">
        <rdfs:label>arthropod</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Invertebrate"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#PhylumArthropodaValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>one arthropod</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ArthropodPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ArthropodPopulation">
        <rdfs:label>arthropod population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Arthropod"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Arthropod"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BacteriaPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BacteriaPopulation">
        <rdfs:label>bacteria population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BacterialCell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BacterialCell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BacterialCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BacterialCell">
        <rdfs:label>bacterial cell</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Cell"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomBacteriaValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Prokaryote"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomBacteriaValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#PlantCell"/>
        <ru-meta:synonym>Bacterium</ru-meta:synonym>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BacterialColony -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BacterialColony">
        <rdfs:label>bacterial colony</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalColony"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BacterialCell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BacterialCell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Cluster of bacteria, usually cultured from a single cell.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BakersYeastCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BakersYeastCell">
        <rdfs:label>bakers yeast cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#YeastCell"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesSaccharomycesCerevisiaeValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#CandidaAlbicansCell"/>
        <rdfs:comment>one saccharomyces cerevisiae cell</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BakersYeastPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BakersYeastPopulation">
        <rdfs:label>bakers yeast population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BakersYeastCell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BakersYeastCell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Behavior -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Behavior">
        <rdfs:label>behavior</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <ru-meta:definition>An (often habitual) action of an organism that is the realization of some disposition</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BioMolecularProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BioMolecularProcess">
        <rdfs:label>bio molecular process</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
        <ru-meta:definition>Process occuring on molecular level. It has exclusivly subclasses of MolecularEntity as participants.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BioMolecularSequenceInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BioMolecularSequenceInformation">
        <rdfs:label>bio molecular sequence information</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SequenceInformation"/>
        <ru-meta:definition>Sequence as an entity of information. The same sequence can inhere in different biopolymers. Sequence information can be theoretical, therefore a &quot;real&quot; sequence is not implied.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BioMolecularSequenceStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BioMolecularSequenceStructure">
        <rdfs:label>bio molecular sequence structure</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidSequence"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ChainOfCarbohydrateMonomers"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ChainOfNucleotideMonomers"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#DNAChain"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#RNAChain"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntity"/>
        <ru-meta:definition>chain (segment) of similar monomers such as proteins or nucleotides</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalAction">
        <rdfs:label>biological action</rdfs:label>
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <ru-meta:definition>Action that has some biological entity as agent</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalBoundary -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalBoundary">
        <rdfs:label>biological boundary</rdfs:label>
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBoundaryOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSpace"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#OneDimensionalPhysicalEntity"/>
        <ru-meta:definition>boundary in or of a biological entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalColony -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalColony">
        <rdfs:label>biological colony</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#PluralityOfOrganisms"/>
        <ru-meta:definition>Plurality of several individual organisms living closely together, usually for mutual benefit</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalFunction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalFunction">
        <rdfs:label>biological function</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Function"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>a function that inheres in some structured biological entity.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalLife -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalLife">
        <rdfs:label>biological life</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismProcess"/>
        <ru-meta:definition>The whole process from origin to death of an organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity">
        <rdfs:label>biological processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Process"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isIncludedIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#PhysicalProcessualEntity"/>
        <ru-meta:definition>Process specific for biological systems.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalSize -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSize">
        <rdfs:label>biological size</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ObjectQuality"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSizeValueRegion"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSizeValueRegion"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>quality of being visible with or without microscope</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalSizeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSizeValueRegion">
        <rdfs:label>biological size value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ValueRegion"/>
        <ru-meta:definition>values that describe the size of biological entities</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalSpace -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSpace">
        <rdfs:label>biological space</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialThreeDimensionalPhysicalEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#isPhysicallyContainedIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>space that is located inside a biological entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiologicalSystemRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSystemRole">
        <rdfs:label>biological system role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <ru-meta:definition>A role specific to biological processes</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BiomedicalMaterialRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BiomedicalMaterialRole">
        <rdfs:label>biomedical material role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#TherapeuticRole"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#DrugRole"/>
        <ru-meta:definition>Role of Non-drug material used for therapeutic Purpose</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Biomolecule -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Biomolecule">
        <rdfs:label>biomolecule</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Monomolecular entity that stems from some organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Bird -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Bird">
        <rdfs:label>bird</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Body -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Body">
        <rdfs:label>body</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
        <ru-meta:definition>Entire biological structure that constitutes a (living) organism. A body can be living or dead. Whether a living organism coincides with its body or hasPart its body, is controversial. We use &quot;hasPhysicalPart&quot; for relating organism to body. Being reflexive, this would not be incompatible with a view in which a living organism is a body.</ru-meta:definition>
        <rdfs:seeAlso>FMAID:256135 Body</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BodyLiquid -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BodyLiquid">
        <rdfs:label>body liquid</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PortionOfHeterogenousLiquid"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#WaterMolecule"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Suspension and / or solution of biomolecules, ions, bigger particles in Water.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#BodySystem -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#BodySystem">
        <rdfs:label>body system</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#OrganismPart"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#Organ"/>
        <ru-meta:definition>Mereological sum of heterogeneous body components that constitute a functional unity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CandidaAlbicansCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CandidaAlbicansCell">
        <rdfs:label>candida albicans cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#YeastCell"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesCandidaAlbicansValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>One candida albicans cell</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CandidaAlbicansPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CandidaAlbicansPopulation">
        <rdfs:label>candida albicans population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CandidaAlbicansCell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CandidaAlbicansCell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CanonicalProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CanonicalProcessualEntity">
        <rdfs:label>canonical processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Process"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#CanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#NoncanonicalProcessualEntity"/>
        <ru-meta:definition>a process that is considered normal</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CanonicalStaticProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CanonicalStaticProcessualEntity">
        <rdfs:label>canonical static processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StaticProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#CanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#NoncanonicalStaticProcessualEntity"/>
        <rdfs:comment>a biological state that is considered &quot;normal&quot;</rdfs:comment>
        <owl:priorVersion>canonical state</owl:priorVersion>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CarbohydrateMoleculeOrResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CarbohydrateMoleculeOrResidue">
        <rdfs:label>carbohydrate molecule or residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CarbohydrateMonomer -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CarbohydrateMonomer">
        <rdfs:label>carbohydrate monomer</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#CarbohydrateMoleculeOrResidue"/>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Monomer"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#ChainOfCarbohydrateMonomers"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CarbohydrateSequenceInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CarbohydrateSequenceInformation">
        <rdfs:label>carbohydrate sequence information</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SequenceInformation"/>
        <ru-meta:definition>The information that describes the make-up of a (physical) carbohydrate sequence.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CatalyticRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CatalyticRole">
        <rdfs:label>catalytic role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ChemicalRole"/>
        <ru-meta:definition>The role a substance plays in accelerating a chemical reaction</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CategorizationSystem -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CategorizationSystem">
        <rdfs:label>categorization system</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#IntellectualProduct"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#RegulationOrLaw"/>
        <ru-meta:definition>A categorization system is a human artifact that aims at partinioning object classes, denotations, or concepts of a given domain.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Causing -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Causing">
        <rdfs:label>causing</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>action that causes an effect</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CellInVivo -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CellInVivo">
        <rdfs:label>cell in vivo</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                </owl:unionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#ModifiedCell"/>
        <ru-meta:definition>Living cell that is not removed from a living system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CellMembrane -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CellMembrane">
        <rdfs:label>cell membrane</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Semipermeable lipid bilayer found in all cells.[1] It contains a wide variety of biological molecules, primarily proteins and lipids, which are involved in a vast array of cellular processes, and also serves as the attachment point for both the intracellular cytoskeleton and, if present, the cell wall.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CellNucleus -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CellNucleus">
        <rdfs:label>cell nucleus</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CentralNervousSystem -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CentralNervousSystem">
        <rdfs:label>central nervous system</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganSystem"/>
        <ru-meta:definition>the central control unit of an organism. Constitutes the brain in higher organisms. </ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ChainOfCarbohydrateMonomers -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ChainOfCarbohydrateMonomers">
        <rdfs:label>chain of carbohydrate monomers</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#CarbohydrateMoleculeOrResidue"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CarbohydrateMonomer"/>
            </owl:Restriction>
        </rdfs:subClassOf>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ChainOfNucleotideMonomers -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ChainOfNucleotideMonomers">
        <rdfs:label>chain of nucleotide monomers</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#NucleicAcidStructure"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ChemicalRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ChemicalRole">
        <rdfs:label>chemical role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <ru-meta:definition>Any role performed by a chemical substance.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ChildRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ChildRole">
        <rdfs:label>child role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilyRole"/>
        <ru-meta:definition>the role an organism plays in relation to its parent</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ChlamydiaCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ChlamydiaCell">
        <rdfs:label>chlamydia cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Prokaryote"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#RickettsiaCell"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Chromosome -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Chromosome">
        <rdfs:label>chromosome</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#MoleculeComplex"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EntireNucleicAcidMolecule"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Organized form of DNA in cells, containing one very long, continuous piece of DNA, which contains many genes, regulatory elements and other intervening nucleotide sequences. Includes also the DNA-bound proteins which serve to package and manage the DNA.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ClassGammaProteobacteriaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ClassGammaProteobacteriaValueRegion">
        <rdfs:label>class gamma proteobacteria value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PhylumProteobacteriaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ClassInsectaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ClassInsectaValueRegion">
        <rdfs:label>class insecta value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PhylumArthropodaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ClassMammaliaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ClassMammaliaValueRegion">
        <rdfs:label>class mammalia value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SubphylumVertebrataValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ClassSaccharomycetesValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ClassSaccharomycetesValueRegion">
        <rdfs:label>class saccharomycetes value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SubphylumSaccharomycotinaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Complicating -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Complicating">
        <rdfs:label>complicating</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>causes to become more severe</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CongenitalAbnormalStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CongenitalAbnormalStructure">
        <rdfs:label>congenital abnormal structure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PathologicalStructure"/>
        <ru-meta:definition>biological structure that deviates from what is considered normal and that already existed at birth</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CongenitalPathologicalCondition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CongenitalPathologicalCondition">
        <rdfs:label>congenital pathological condition</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PathologicalValueRegion"/>
        <ru-meta:definition>Ill-formed state of a biological entity, present from birth [steschu 20071010]</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#CongenitalPathologicalStaticProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#CongenitalPathologicalStaticProcessualEntity">
        <rdfs:label>congenital pathological static processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#PathologicalStaticProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CongenitalPathologicalCondition"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:priorVersion>congenital pathological state</owl:priorVersion>
        <ru-meta:definition>pathological state present at birth</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Cytoplasm -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Cytoplasm">
        <rdfs:label>cytoplasm</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#WaterMolecule"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Gelatinous, semi-transparent fluid that fills most cells. E</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#DNAChain -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#DNAChain">
        <rdfs:label>DNA chain</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ChainOfNucleotideMonomers"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#RNAChain"/>
        <ru-meta:definition>A DNA is a complex, high-molecular-weight biochemical macromolecule composed of deoxyribonumcleotide chains that convey genetic information. Any kind of NucleicAcid that is composed of Deoxyribonucleotides is here defined as DNA.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#DeadBody -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#DeadBody">
        <rdfs:label>dead body</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Body"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#LivingBody"/>
        <ru-meta:definition>body that is the transformation of a living body after death</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Death -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Death">
        <rdfs:label>death</rdfs:label>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
                    <owl:Class>
                        <owl:complementOf>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasDuration"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#TimeInterval"/>
                            </owl:Restriction>
                        </owl:complementOf>
                    </owl:Class>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasPointInTime"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#PointInTime"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>End of live of a biological system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#DevelopmentalQuality -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#DevelopmentalQuality">
        <rdfs:label>developmental quality</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ObjectQuality"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Ontogenetic stage</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion">
        <rdfs:label>developmental value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ValueRegion"/>
        <ru-meta:definition>abstract region in which the values of developmental stages are located</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#DigitalEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#DigitalEntity">
        <rdfs:label>digital entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <ru-meta:definition>any kind of information that is fully expressible by a sequence of binary values.</ru-meta:definition>
        <rdfs:comment>(OBI 306)</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Disrupting -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Disrupting">
        <rdfs:label>disrupting</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>Producing a negative effect on</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#DrugRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#DrugRole">
        <rdfs:label>drug role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#TherapeuticRole"/>
        <ru-meta:definition>The role of a chemical of biological entity of being deliberately used in virtue of its expected positive impact on a dysfunctional biological system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EducatorRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EducatorRole">
        <rdfs:label>educator role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OccupationalRole"/>
        <ru-meta:definition>The role a person plays that is occupied by educational activities</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Eicosanoid -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Eicosanoid">
        <rdfs:label>eicosanoid</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue"/>
        <ru-meta:definition>An oxygenated metabolite from polyunsaturated 20 carbon fatty acids including lipoxygenase and cyclooxygenase products and their synthetic analogs. This includes the prostaglandins and thromboxanes. (UMLS SN)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Electron -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Electron">
        <rdfs:label>electron</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#SubAtomicParticle"/>
        <ru-meta:definition>Negatively Charged Particle</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EmbryonicOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicOrganism">
        <rdfs:label>embryonic organism</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#DevelopmentalQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EmbryonicValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismByDevelopmentalStagePartition"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#JuvenileOrganism"/>
        <ru-meta:definition>evolving organism before birth, with not yet fully formed organs</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EmbryonicStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicStructure">
        <rdfs:label>embryonic structure</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicOrganism"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EmbryonicOrganism"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#DevelopmentalQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EmbryonicValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>An embryo or any structure derived from it. There may be structures derived from an embryo that are no longer considered embryonic ones, hence no full definition.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EmbryonicValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicValueRegion">
        <rdfs:label>embryonic value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion"/>
        <rdfs:comment>&quot;embryonic&quot; as the value of a developmental stage. E.g. a 3 days old mouse embryo has a quality which has its value located in &quot;embryonic value region&quot;.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EntireCarbohydrateMonomer -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EntireCarbohydrateMonomer">
        <rdfs:label>entire carbohydrate monomer</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#CarbohydrateMonomer"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EntireMolecularEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EntireMolecularEntity">
        <rdfs:label>entire molecular entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#MolecularResidue"/>
        <ru-meta:definition>Separately distinguishable molecular structure, neither part of nor attached to any other molecular structure. Atoms are not considered molecular structures. The hierarchy of entire entities mirrors the hierarchy of structures.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EntireNucleicAcidMolecule -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EntireNucleicAcidMolecule">
        <rdfs:label>entire nucleic acid molecule</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#EntireMolecularEntity"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Monomer"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>not (properPartOf some MonoMolecularEntity)  REMOVED</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EntireProteinMolecule -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EntireProteinMolecule">
        <rdfs:label>entire protein molecule</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
        <ru-meta:definition>Amino Acid Polymer longer than 100 monomers.</ru-meta:definition>
        <rdfs:comment>(QCR) Peptide and hasComponent min 101 AminoAcidMonomer and not (ro:properPartOf some MolecularEntity)</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EnzymeRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EnzymeRole">
        <rdfs:label>enzyme role</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#CatalyticRole"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#RNAChain"/>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>The role a peptide plays in accelerating a biochemical reaction</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EpithelialCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EpithelialCell">
        <rdfs:label>epithelial cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EscherichiaColiCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EscherichiaColiCell">
        <rdfs:label>escherichia coli cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BacterialCell"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesEscherichiaColiValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EscherichiaColiPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EscherichiaColiPopulation">
        <rdfs:label>escherichia coli population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EscherichiaColiCell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EscherichiaColiCell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Eukaryote -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Eukaryote">
        <rdfs:label>eukaryote</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismByTaxonPartition"/>
        <ru-meta:definition>An eukaryote is an organism with a complex cell or cells, in which the genetic material is organized into a membrane-bound nucleus or nuclei. Most Eukaryots are multicellular, haowever, there are some which are always unicellular (protists, some fungi) but there are also unicellular developmental stages (zygotes) of plants and animals.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#EukaryotePopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#EukaryotePopulation">
        <rdfs:label>eukaryote population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ExaminationResultRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ExaminationResultRole">
        <rdfs:label>examination result role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FindingRole"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#SignOrSymptomRole"/>
        <ru-meta:definition>The role a measurement plays if it has been produced in the context of the quantitative assessment of a biological system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FamilyDrosophilidaeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FamilyDrosophilidaeValueRegion">
        <rdfs:label>family drosophilidae value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrderDipteraValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FamilyEnterobacteriaceaeaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FamilyEnterobacteriaceaeaValueRegion">
        <rdfs:label>family enterobacteriaceaea value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrderEnterobacterialesValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FamilyHominidaeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FamilyHominidaeValueRegion">
        <rdfs:label>family hominidae value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrderPrimatesValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FamilyRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FamilyRole">
        <rdfs:label>family role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AnimalPopulation"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FamilySaccharomycetaceaeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FamilySaccharomycetaceaeValueRegion">
        <rdfs:label>family saccharomycetaceae value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrderSaccharomycetalesValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FattyAcidMoleculeOrResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FattyAcidMoleculeOrResidue">
        <rdfs:label>fatty acid molecule or residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Carboxylic acid often with a long unbranched aliphatic tail.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FindingRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FindingRole">
        <rdfs:label>finding role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
        <ru-meta:definition>The role that may inhere in any biological structure, state, or process that is of reportable interest in a diagnostic process.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Fish -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Fish">
        <rdfs:label>fish</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FoodRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FoodRole">
        <rdfs:label>food role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
        <ru-meta:definition>The role of an entity components of which are used for supplying energy and vital substrates to a biological system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FruitFly -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FruitFly">
        <rdfs:label>fruit fly</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Insect"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesDrosophilaMelanogasterValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>one drosophila melanogaster</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FruitFlyPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FruitFlyPopulation">
        <rdfs:label>fruit fly population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#FruitFly"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#FruitFly"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Fungus -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Fungus">
        <rdfs:label>fungus</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomFungiValueRegion"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomFungiValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>On fungus organisms</rdfs:comment>
        <ru-meta:definition>Heterotrophic organisms characterized by a chitinous cell wall.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#FungusPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#FungusPopulation">
        <rdfs:label>fungus population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Fungus"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Fungus"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GaseousValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GaseousValueRegion">
        <rdfs:label>gaseous value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion"/>
        <rdfs:comment>&quot;gaseous&quot; as the value of a states of matter.  E.g. a portion of air has a quality which has its value located in &quot;gaseous value region&quot;</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Gene -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Gene">
        <rdfs:label>gene</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#NucleicAcidStructure"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#GeneticInformation"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:versionInfo>TODO: Discuss whether all genes are DNA !</owl:versionInfo>
        <ru-meta:definition>region of nucleic acid macromolecule that carry information</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GeneInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GeneInformation">
        <rdfs:label>gene information</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <ru-meta:definition>Information that resides on a gene.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GeneticInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GeneticInformation">
        <rdfs:label>genetic information</rdfs:label>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#InformationObject"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ChainOfNucleotideMonomers"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Gene"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Genome"/>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>information that can be interpreted by a genetic code</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Genome -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Genome">
        <rdfs:label>genome</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#GeneticInformation"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>sum of genetic material in a cell</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GenomeInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GenomeInformation">
        <rdfs:label>genome information</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <ru-meta:definition>The totality of hereditary information of an organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GenusCandidaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GenusCandidaValueRegion">
        <rdfs:label>genus candida value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilySaccharomycetaceaeValueRegion"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#GenusSaccharomycesValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GenusDrosophilaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GenusDrosophilaValueRegion">
        <rdfs:label>genus drosophila value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SubfamilyDrosophilinaeValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GenusEscherichiaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GenusEscherichiaValueRegion">
        <rdfs:label>genus escherichia value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilyEnterobacteriaceaeaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GenusHomoValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GenusHomoValueRegion">
        <rdfs:label>genus homo value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilyHominidaeValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GenusSaccharomycesValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GenusSaccharomycesValueRegion">
        <rdfs:label>genus saccharomyces value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilySaccharomycetaceaeValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GeographicSurface -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GeographicSurface">
        <rdfs:label>geographic surface</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TwoDimensionalPhysicalEntity"/>
        <rdfs:comment>previous name &quot;geographic entity&quot;</rdfs:comment>
        <ru-meta:definition>delineated surface of a large solid body in space (earth, moon, sun,...)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Government -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Government">
        <rdfs:label>government</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Organization"/>
        <ru-meta:definition>entity governing a defined group of people</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GreatApe -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GreatApe">
        <rdfs:label>great ape</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Mammal"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#FamilyHominidaeValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>one great ape</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GreatApePopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GreatApePopulation">
        <rdfs:label>great ape population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#GreatApe"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#GreatApe"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GroupInteraction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GroupInteraction">
        <rdfs:label>group interaction</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Interacting"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LegalEntity"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>action in which physical or legal groups interact</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#GrowingProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#GrowingProcess">
        <rdfs:label>growing process</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#TissueProcess"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HealthProfessionalRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HealthProfessionalRole">
        <rdfs:label>health professional role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OccupationalRole"/>
        <ru-meta:definition>the role a human plays as active part in a health system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HealthRelatedRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HealthRelatedRole">
        <rdfs:label>health related role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <ru-meta:definition>A role an entity plays as an actor or participant in processes that assess or influence the health status of an organism.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HeterocyclicBaseMoleculeOrResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HeterocyclicBaseMoleculeOrResidue">
        <rdfs:label>heterocyclic base molecule or residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Organic compounds that contain a ring structure containing N as proton receptor. Important parts of DNA and RNA molecules.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HormoneRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HormoneRole">
        <rdfs:label>hormone role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SignallingRole"/>
        <ru-meta:definition>The role a biologically active substance plays when it participates in the transmission of messages across a certain distance in an organism.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Human -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Human">
        <rdfs:label>human</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Primate"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesHomoSapiensValueRegion"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesHomoSapiensValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HumanAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HumanAction">
        <rdfs:label>human action</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismAction"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Human"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Action that has some human as agent</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HumanEpithelialCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HumanEpithelialCell">
        <rdfs:label>human epithelial cell</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#EpithelialCell"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                        <owl:someValuesFrom>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SpeciesHomoSapiensValueRegion"/>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HumanLanguage -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HumanLanguage">
        <rdfs:label>human language</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LanguagePartition"/>
        <ru-meta:definition>language used in communication between non-human animals</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HumanPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HumanPopulation">
        <rdfs:label>human population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#HumanReasoning -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#HumanReasoning">
        <rdfs:label>human reasoning</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HumanAction"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasOutcome"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#IntellectualProduct"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HumanAction"/>
        <ru-meta:definition>Process in which a human creates an intellectual product</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Hurting -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Hurting">
        <rdfs:label>hurting</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ActionOnBiologicalSystem"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#PhysicalForce"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>negatively affecting a biological system by using physical force</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ImmaterialProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ImmaterialProcessualEntity">
        <rdfs:label>immaterial processual entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
        <ru-meta:definition>A process with non-material participants, e.g. legal or organizational entities or information objects</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ImmunologicRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ImmunologicRole">
        <rdfs:label>immunologic role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSystemRole"/>
        <ru-meta:definition>A role that is played by any biological entity in virtue of the defense of an organism against infective agents</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Indicating -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Indicating">
        <rdfs:label>indicating</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>action that indicates something</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#IndicatorRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#IndicatorRole">
        <rdfs:label>indicator role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ChemicalRole"/>
        <ru-meta:definition>A role a chemical plays for measuring or analyzing other chemical processes</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#IndividualBehavior -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#IndividualBehavior">
        <rdfs:label>individual behavior</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Behavior"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#SocialBehavior"/>
        <ru-meta:definition>Behavior of an individual organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#InorganicMolecularEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#InorganicMolecularEntity">
        <rdfs:label>inorganic molecular entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntity"/>
        <ru-meta:definition>Substances which do not include carbon and its derivatives as their principal elements. However, carbides, carbonates, cyanides, cyanates and carbon disulfide are included in this class.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Insect -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Insect">
        <rdfs:label>insect</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Arthropod"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#ClassInsectaValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>one insect</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#InsectPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#InsectPopulation">
        <rdfs:label>insect population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Insect"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Insect"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#IntellectualProduct -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#IntellectualProduct">
        <rdfs:label>intellectual product</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isPatientIn"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Process"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>An intellectual product is a piece of information that is the outcome of a human reasoning process</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Interacting -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Interacting">
        <rdfs:label>interacting</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#GroupInteraction"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#OrganismInteraction"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#SubstanceInteraction"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>two or more interaction partners exerce a mutual effect that may lead to structural transformation.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#IntraCellularProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#IntraCellularProcess">
        <rdfs:label>intra cellular process</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isIncludedIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Process occuring in a cell.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Invertebrate -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Invertebrate">
        <rdfs:label>invertebrate</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#JuvenileOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#JuvenileOrganism">
        <rdfs:label>juvenile organism</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#DevelopmentalQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#JuvenileValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismByDevelopmentalStagePartition"/>
        <ru-meta:definition>born organism, not yet in reproductive age</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#JuvenileValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#JuvenileValueRegion">
        <rdfs:label>juvenile value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#DevelopmentalValueRegion"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion">
        <rdfs:label>kingdom animalia value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomArchaeaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomArchaeaValueRegion">
        <rdfs:label>kingdom archaea value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomBacteriaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomBacteriaValueRegion">
        <rdfs:label>kingdom bacteria value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomChromistaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomChromistaValueRegion">
        <rdfs:label>kingdom chromista value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomFungiValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomFungiValueRegion">
        <rdfs:label>kingdom fungi value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomPlantaeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomPlantaeValueRegion">
        <rdfs:label>kingdom plantae value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomProtozoaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomProtozoaValueRegion">
        <rdfs:label>kingdom protozoa value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#KingdomVirusesValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#KingdomVirusesValueRegion">
        <rdfs:label>kingdom viruses value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Language -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Language">
        <rdfs:label>language</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <ru-meta:definition>system of signs used for communication between biological and / or machine agents</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#LanguagePartition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#LanguagePartition">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Language"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AnimalLanguage"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HumanLanguage"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#MachineLanguage"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Ontologically irrelevant partitioning node. Used for improving ontology housekeeping. Its purpose is to express that all subclasses are mutually disjoint.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#LegalEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#LegalEntity">
        <rdfs:label>legal entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <ru-meta:definition>nonmaterial entity that as an existence in a legal system</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue">
        <rdfs:label>lipid molecule or residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Fat-soluble (lipophilic), naturally-occurring molecule.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#LiquidValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#LiquidValueRegion">
        <rdfs:label>liquid value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion"/>
        <rdfs:comment>&quot;liquid&quot; as the value of a states of matter. E.g. a portion of water has a quality which has its value located in &quot;liquid value region&quot;</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#LivingBody -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#LivingBody">
        <rdfs:label>living body</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Body"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isParticipantIn"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalLife"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                </owl:unionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>Entirety of the biological structure that constitutes a living organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#LivingOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism">
        <rdfs:label>living organism</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Organism"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isParticipantIn"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalLife"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:priorVersion>organism</owl:priorVersion>
        <ru-meta:definition>Living complex biological system which functions as a stable whole. In contrast to colonial organisms their components generally cannot survive on their own. We conceive organisms in a material sense. Therefore we do not assume any ontological difference between a unicellular organism and the cell it is made of. &quot;Colonial Organism&quot; are not considered Organisms. We here include viruses into the category of organisms.

Organism in an inactive form which are not dead are considered living organisms.

Whether a living organism coincides with its body or hasPart its body, is controversial. We use &quot;hasPhysicalPart&quot; for relating organism to body. Being reflexive, this would not be incompatible with a view in which a living organism is a body.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MachineAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MachineAction">
        <rdfs:label>machine action</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Action"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#ArtefactRole"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>An action performed by a machine. A machine is here seen as a non-biological artifact.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MachineLanguage -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MachineLanguage">
        <rdfs:label>machine language</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LanguagePartition"/>
        <ru-meta:definition>language used for processing by machines</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MacroscopicValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MacroscopicValueRegion">
        <rdfs:label>macroscopic value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSizeValueRegion"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
        <ru-meta:definition>size values of objects that are visible to the naked eye</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Mammal -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Mammal">
        <rdfs:label>mammal</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#ClassMammaliaValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>one mammal</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MammalPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MammalPopulation">
        <rdfs:label>mammal population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Mammal"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Mammal"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ManagingCare -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ManagingCare">
        <rdfs:label>managing care</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Human"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LegalEntity"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Human"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>action in which a subject cares for the well-being of some biological entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Measure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Measure">
        <rdfs:label>measure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <ru-meta:definition>Numeric quantity or cardinality, reference for measurement processes. Example kilogram, hour, ampere.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MeasurementMethod -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MeasurementMethod">
        <rdfs:label>measurement method</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Plan"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasRealization"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MeasuringAction"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Plan"/>
        <ru-meta:definition>Plan that is realized by a measurement process.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MeasuringAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MeasuringAction">
        <rdfs:label>measuring action</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <ru-meta:definition>an action that aims at producing a measurement</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Membership -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Membership">
        <rdfs:label>membership</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ImmaterialProcessualEntity"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasPatient"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LegalEntity"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Human"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LegalEntity"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Process that endures while something or some person is part of a legal entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MentalFunction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MentalFunction">
        <rdfs:label>mental function</rdfs:label>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalFunction"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CentralNervousSystem"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>biological function ascribed to the behavioral manisfestations of the brain</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MentalProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MentalProcess">
        <rdfs:label>mental process</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismProcess"/>
        <rdfs:comment>process in an organism as a realization of a mental function</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Microorganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Microorganism">
        <rdfs:label>microorganism</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
                            </owl:Restriction>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
        <ru-meta:definition>organism that can be seen only through a microscope</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MicroscopicValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion">
        <rdfs:label>microscopic value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSizeValueRegion"/>
        <ru-meta:definition>size values of objects that are too small to be seen without a microscope</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Mind -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Mind">
        <rdfs:label>mind</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
        <rdfs:comment>Difficult concept. Better to be expressed by the primitive &quot;mental function&quot; </rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ModifiedCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ModifiedCell">
        <rdfs:label>modified cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                </owl:complementOf>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#derivesFrom"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CellInVivo"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Cells that grow and replicate continuously outside the living organism.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MolecularFunction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MolecularFunction">
        <rdfs:label>molecular function</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Function"/>
        <ru-meta:definition>Inherent function of a single molecule.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MolecularResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MolecularResidue">
        <rdfs:label>molecular residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <ru-meta:definition>not self-standing aggregation of atoms which are part of a bigger molecule</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MoleculeComplex -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MoleculeComplex">
        <rdfs:label>molecule complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#PolyMolecularCompositeEntity"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EntireMolecularEntity"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Particle that consists of entire molecules.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Monomer -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Monomer">
        <rdfs:label>monomer</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#OligoOrPolymer"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
        <ru-meta:definition>Monomers can be described as constituted by molecularl groups. They are not repetitive and can constitute the building blocks of Polymers.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#MulticellularOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#MulticellularOrganism">
        <rdfs:label>multicellular organism</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#DevelopmentalQuality"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Organisms that are composed by more than one cell.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NeoplasticProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NeoplasticProcess">
        <rdfs:label>neoplastic process</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#GrowingProcess"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NeuroreactiveRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NeuroreactiveRole">
        <rdfs:label>neuroreactive role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SignallingRole"/>
        <ru-meta:definition>A role a molecule plays if it acts as a neurotransmitter</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Neutron -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Neutron">
        <rdfs:label>neutron</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#SubAtomicParticle"/>
        <ru-meta:synonym>Neutral Particle</ru-meta:synonym>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NonSteroidLipid -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NonSteroidLipid">
        <rdfs:label>non steroid lipid</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue"/>
        <ru-meta:definition>Lipids that have aliphatic chains and no steroid rings</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NoncanonicalProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NoncanonicalProcessualEntity">
        <rdfs:label>noncanonical processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Process"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>a process that is considered abnormal</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NoncanonicalStaticProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NoncanonicalStaticProcessualEntity">
        <rdfs:label>noncanonical static processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StaticProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>a biological state that is considered &quot;abnormal&quot;</ru-meta:definition>
        <owl:priorVersion>noncanonical state</owl:priorVersion>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NucleicAcidNucleotideOrNucleosideMoleculeOrResidue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NucleicAcidNucleotideOrNucleosideMoleculeOrResidue">
        <rdfs:label>nucleic acid nucleotide or nucleoside molecule or residue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NucleicAcidStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NucleicAcidStructure">
        <rdfs:label>nucleic acid structure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#NucleicAcidNucleotideOrNucleosideMoleculeOrResidue"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#NucleotideMolecule"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#NucleotideMolecule"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>A nucleic acid is a complex, high-molecular-weight biochemical macromolecule composed of nucleotide chains that convey genetic information.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NucleosideMolecule -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NucleosideMolecule">
        <rdfs:label>nucleoside molecule</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#NucleicAcidNucleotideOrNucleosideMoleculeOrResidue"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition></ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NucleotideMolecule -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NucleotideMolecule">
        <rdfs:label>nucleotide molecule</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#NucleicAcidNucleotideOrNucleosideMoleculeOrResidue"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Comment: (QCR) hasComponent exactly 1 HeterocyclicBase and hasComponent exactly 1 Phosphate and hasComponent only (Phosphate or Ribose or HeterocyclicBase) and hasComponent exactly 1 Pentose</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NucleotideSequenceInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NucleotideSequenceInformation">
        <rdfs:label>nucleotide sequence information</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SequenceInformation"/>
        <ru-meta:definition>The information that describes the make-up of a (physical) nucleotide sequence.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#NurseRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#NurseRole">
        <rdfs:label>nurse role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthProfessionalRole"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#PhysicianRole"/>
        <ru-meta:definition>The role a nurse plays</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ObservingAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ObservingAction">
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OccupationalRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OccupationalRole">
        <rdfs:label>occupational role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <ru-meta:definition>The role that determines the occupation that characterizes the daily life of a human being or animal.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OligoOrPolymer -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OligoOrPolymer">
        <rdfs:label>oligo or polymer</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Monomer"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Monomer"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#SubmolecularGroup"/>
        <ru-meta:definition>An oligo or polymer macromolecular structure is a molecule of moderate to high relative molecular mass, the structure of which essentially comprises the multiple repetition (n &gt;= 2) of units derived from molecules of low relative molecular mass.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OneDimensionalBoundary -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OneDimensionalBoundary">
        <rdfs:label>one dimensional boundary</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#OneDimensionalPhysicalEntity"/>
        <ru-meta:definition>line bounding a two-dimensional biological entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrderDipteraValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrderDipteraValueRegion">
        <rdfs:label>order diptera value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ClassInsectaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrderEnterobacterialesValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrderEnterobacterialesValueRegion">
        <rdfs:label>order enterobacteriales value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ClassGammaProteobacteriaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrderPrimatesValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrderPrimatesValueRegion">
        <rdfs:label>order primates value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ClassMammaliaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrderSaccharomycetalesValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrderSaccharomycetalesValueRegion">
        <rdfs:label>order saccharomycetales value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ClassSaccharomycetesValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Organ -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Organ">
        <rdfs:label>organ</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#OrganismPart"/>
        <ru-meta:definition>Macroscopic, well delimited, functionally and structurally characterized part of an organism. Exact criteria of what an organ is do not exist.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganPart -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganPart">
        <rdfs:label>organ part</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#OrganismPart"/>
        <rdfs:seeAlso>FMAID:82472 Cardinal organ part</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganSystem -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganSystem">
        <rdfs:label>organ system</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BodySystem"/>
        <rdfs:seeAlso>FMAID:7149 Organ system</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganSystemPart -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganSystemPart">
        <rdfs:label>organ system part</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BodySystem"/>
        <rdfs:seeAlso>FMAID:67509  Organ system subdivistion</rdfs:seeAlso>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganicMolecularEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganicMolecularEntity">
        <rdfs:label>organic molecular entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <ru-meta:definition>Substances containing carbon and its derivatives as their prinicipal elements, usually combined with itself and with atoms of one or more other element such as hydrogen, oxygen, nitrogen, sulfur, phosphorus, chlorine or fluorine. They exist in either carbon chain or carbon ring form. Excludes carbides, carbonates and carbon oxides.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganicMolecularEntityPartition">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#OrganicMolecularEntity"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidOrPeptideMoleculeOrStructure"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#CarbohydrateMoleculeOrResidue"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#FattyAcidMoleculeOrResidue"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HeterocyclicBaseMoleculeOrResidue"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#NucleicAcidNucleotideOrNucleosideMoleculeOrResidue"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>Ontologically irrelevant partitioning node. Used for improving ontology housekeeping. Its purpose is to express that all subclasses are mutually disjoint.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganismAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganismAction">
        <rdfs:label>organism action</rdfs:label>
        <owl:equivalentClass>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalAction"/>
        <ru-meta:definition>Action that has some organism as agent</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganismByDevelopmentalStagePartition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganismByDevelopmentalStagePartition">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AdultOrganism"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicOrganism"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#JuvenileOrganism"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AdultOrganism"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicOrganism"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#JuvenileOrganism"/>
                </owl:unionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>Ontologically irrelevant partitioning node. Used for improving ontology housekeeping. Its purpose is to express that all subclasses are mutually disjoint.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganismByTaxonPartition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganismByTaxonPartition">
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Eukaryote"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Prokaryote"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Virus"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>Ontologically irrelevant partitioning node. Used for improving ontology housekeeping. Its purpose is to express that all subclasses are mutually disjoint.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganismInteraction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganismInteraction">
        <rdfs:label>organism interaction</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Interacting"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>action in which single biological organisms interact</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganismPart -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganismPart">
        <rdfs:label>organism part</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Tissue"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MulticellularOrganism"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#Syncytium"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
        <ru-meta:definition>A well defined and circumscribed subdivision of an organism, not any arbitrary part. Macroscopic organism parts may be delimited mainly by natural boundaries but always exhibit at least small regions of fiat boundaries. An organism part may derive from an organism, i.e. it may continue to exist even when the organism does not exist any longer.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#OrganismProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#OrganismProcess">
        <rdfs:label>organism process</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>any biological process that involves a whole organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Organization -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Organization">
        <rdfs:label>organization</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LegalEntity"/>
        <ru-meta:definition>collection of human or legal entities</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ParentRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ParentRole">
        <rdfs:label>parent role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilyRole"/>
        <ru-meta:definition>the role an organism plays in relation to its children</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PathologicalCondition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PathologicalCondition">
        <rdfs:label>pathological condition</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#PathologicalDisposition"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#PathologicalProcess"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#PathologicalStructure"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Condition"/>
        <ru-meta:definition>pathological structure, disposition, or process. This disjoint category helps properly represent diseases becauses it is often left open whether they are meant as pathological structure, disposition, or process.

In case this is to be left open, the relation has_locus should be used to connect them to anatomical entities</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PathologicalDisposition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PathologicalDisposition">
        <rdfs:label>pathological disposition</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Disposition"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>any kind of disposition considered non-canonical. The criteria of canonicity are not further specified. 
The classification of certain dispositions as dysfunctional or pathological is dependent on a historic and cultural context. Dysfunction or disease therefore hasn&apos;t the status of a universal.</ru-meta:definition>
        <owl:priorVersion>prior label &quot;dysfunction&quot;</owl:priorVersion>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PathologicalProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PathologicalProcess">
        <rdfs:label>pathological process</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>a biological process which is non-canonic</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PathologicalStaticProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PathologicalStaticProcessualEntity">
        <rdfs:label>pathological static processual entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
                                    </owl:Restriction>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#PathologicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#NoncanonicalStaticProcessualEntity"/>
        <owl:priorVersion>pathological state</owl:priorVersion>
        <rdfs:comment>Condition of an organism that deviates from what is considered normal. Often referred to by the terms &quot;disorder&quot;, &quot;disease&quot;, &quot;syndrome&quot;, &quot;sign&quot;, or &quot;symptom&quot;. None of these denote clearly delineated ontological categories. 

See disease role etc.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PathologicalStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PathologicalStructure">
        <rdfs:label>pathological structure</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#WellFormedBiologicalStructure"/>
        <owl:priorVersion>former name: &quot;ill formed biological structure&quot;</owl:priorVersion>
        <ru-meta:definition>biological structure that is non-canonic</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PathologicalValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PathologicalValueRegion">
        <rdfs:label>pathological value region</rdfs:label>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                                        <owl:someValuesFrom>
                                            <owl:Class>
                                                <owl:unionOf rdf:parseType="Collection">
                                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#OrganismPart"/>
                                                </owl:unionOf>
                                            </owl:Class>
                                        </owl:someValuesFrom>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isProjectionOf"/>
                                <owl:someValuesFrom>
                                    <owl:Class>
                                        <owl:intersectionOf rdf:parseType="Collection">
                                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                            <owl:Restriction>
                                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                                                <owl:someValuesFrom>
                                                    <owl:Class>
                                                        <owl:unionOf rdf:parseType="Collection">
                                                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                                                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#OrganismPart"/>
                                                        </owl:unionOf>
                                                    </owl:Class>
                                                </owl:someValuesFrom>
                                            </owl:Restriction>
                                        </owl:intersectionOf>
                                    </owl:Class>
                                </owl:someValuesFrom>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>state of an organism or an organism part requiring therapeutic or palliative intervention</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PeptideFunction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PeptideFunction">
        <rdfs:label>peptide function</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#MolecularFunction"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Inherent Function of a protein or a part of it.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PeptideStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PeptideStructure">
        <rdfs:label>peptide structure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#AminoAcidOrPeptideMoleculeOrStructure"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#AminoAcidMoleculeOrResidue"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>Comment: We here use the term peptide in the most general sense, viz. a oligo or polymer made out of amino acids.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Phosphate -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Phosphate">
        <rdfs:label>phosphate</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#InorganicMolecularEntity"/>
        <ru-meta:definition>Phosphate is a salt of phosphoric acid or a functional group on organic compounds.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhylumArthropodaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhylumArthropodaValueRegion">
        <rdfs:label>phylum arthropoda value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion"/>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/biotop.owl#PhylumChordataValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhylumAscomycotaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhylumAscomycotaValueRegion">
        <rdfs:label>phylum ascomycota value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#KingdomFungiValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhylumChordataValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhylumChordataValueRegion">
        <rdfs:label>phylum chordata value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#KingdomAnimaliaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhylumProteobacteriaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhylumProteobacteriaValueRegion">
        <rdfs:label>phylum proteobacteria value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#KingdomBacteriaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhysicalProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhysicalProcessualEntity">
        <rdfs:label>physical processual entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>process that only involves non-biological participants</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhysicalState -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhysicalState">
        <rdfs:label>physical state</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ObjectQuality"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Quality of being solid, liquid, gaseous, ...  [steschu20080127]</ru-meta:definition>
        <rdfs:comment>former name: StateOfAggregation</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PhysicianRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PhysicianRole">
        <rdfs:label>physician role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthProfessionalRole"/>
        <ru-meta:definition>The role a physician plays</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Plant -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Plant">
        <rdfs:label>plant</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomPlantaeValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Organism of the kingdom Plantae.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PlantCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PlantCell">
        <rdfs:label>plant cell</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Cell"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#KingdomPlantaeValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PlantPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PlantPopulation">
        <rdfs:label>plant population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Plant"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Plant"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PoisonRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PoisonRole">
        <rdfs:label>poison role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
        <ru-meta:definition>The role of a substance of mixture of substance of a defined amount thereof to be toxic to (parts of) biological organisms</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Poisoning -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Poisoning">
        <rdfs:label>poisoning</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ActionOnBiologicalSystem"/>
        <rdfs:comment>negatively affecting the integrity of a biologival system caused by one or more chemical substances</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Population -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Population">
        <rdfs:label>population</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#PluralityOfOrganisms"/>
        <rdfs:comment>all child classes of population are only meant as examples demonstrating how population classes can be postcoordinated</rdfs:comment>
        <ru-meta:definition>Collection of Organisms of a defined taxon living in a given geographic area. In contrast to the &quot;official&quot; definition (&quot;same species&quot;) this definition is broader and corresponds better to the use of the term in some contexts (e.g. &quot;mixed population of 2 species&quot;)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PortionOfHeterogenousLiquid -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PortionOfHeterogenousLiquid">
        <rdfs:label>portion of heterogenous liquid</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#CompoundOfCollectiveMaterialEntities"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LiquidValueRegion"/>
                            </owl:Restriction>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Liquid constituted by different kinds of collectives, e.g. aqueous NaCl solution</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PortionOfHeterogenousSolid -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PortionOfHeterogenousSolid">
        <rdfs:label>portion of heterogenous solid</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#CompoundOfCollectiveMaterialEntities"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SolidValueRegion"/>
                            </owl:Restriction>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Solid constituted by different kinds of collectives, e.g. a NaCl crystal, granite</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PreventionAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PreventionAction">
        <rdfs:label>prevention action</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasPatient"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <ru-meta:definition>Hinders a  process or the realization of a  function. As the second argument represents sth non-existent, it cannot be expressed in FOL. Hence the special status of this class. (Cf. Condovardi et al. &quot;Preventing Existence, FOIS 2001)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PreventiveRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PreventiveRole">
        <rdfs:label>preventive role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
        <ru-meta:definition>The role an action plays if it is intended to protect an organism against negative external influences.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Primate -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Primate">
        <rdfs:label>primate</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#GreatApe"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#OrderPrimatesValueRegion"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#OrderPrimatesValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>one primate</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#PrimatePopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#PrimatePopulation">
        <rdfs:label>primate population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Primate"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Primate"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Producing -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Producing">
        <rdfs:label>producing</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>action in which a new physical or informational entity comes into being</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Prokaryote -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Prokaryote">
        <rdfs:label>prokaryote</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismByTaxonPartition"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Cell lacking membrane enclosed organells</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ProteinComplex -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ProteinComplex">
        <rdfs:label>protein complex</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#MoleculeComplex"/>
        <ru-meta:definition>Mostly only proteins but composition with other molecules possible (e.g. Fe -&gt; Hemoglobin) or also lipoproteins</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ProteinDomain -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ProteinDomain">
        <rdfs:label>protein domain</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EntireProteinMolecule"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Structural domain is the smallest element of protein tertiary structure that is self-stabilizing and often folds independently of the rest of the amino acid chain. It may contain one or more structural motives (ProteinSubstructure). A protein domain typically has its own function, the overall function of the protein results from the composition of the functions of all of its structural domains.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ProteinSubstructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ProteinSubstructure">
        <rdfs:label>protein substructure</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PeptideStructure"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EntireProteinMolecule"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>A secondary substructure of a protein (protein Motif)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ProteinSubunit -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ProteinSubunit">
        <rdfs:label>protein subunit</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#EntireProteinMolecule"/>
        <ru-meta:definition>A protein molecule that assembles with other protein molecules to form a protein complex. May have its own function. However, most proteinsubunits do not gain functionality until associated with the other subunits.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Protist -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Protist">
        <rdfs:label>protist</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Eukaryote"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Organisms of the kingdom Protista</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ProtistPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ProtistPopulation">
        <rdfs:label>protist population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Protist"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Protist"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Proton -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Proton">
        <rdfs:label>proton</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#SubAtomicParticle"/>
        <ru-meta:definition>Positively Charged Particle</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#RNAChain -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#RNAChain">
        <rdfs:label>RNA chain</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ChainOfNucleotideMonomers"/>
        <ru-meta:definition>any kind of NucleicAcid that is composed of Ribonucleotides which are not Deoxyribonucleotides</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Radiation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Radiation">
        <rdfs:label>radiation</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MaterialObject"/>
        <ru-meta:definition>process in which energy-rich particles or electromagnetic waves participate</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ReagentRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ReagentRole">
        <rdfs:label>reagent role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#ChemicalRole"/>
        <ru-meta:definition>A role a chemical plays as participant in a chemical reation</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ReceptorRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ReceptorRole">
        <rdfs:label>receptor role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#SignallingRole"/>
        <ru-meta:definition>The role a (membrane) protein or protein complex plays in acting as a receptor.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#RegulationOrLaw -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#RegulationOrLaw">
        <rdfs:label>regulation or law</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#IntellectualProduct"/>
        <ru-meta:definition>set of rules governing a particular kind of activity (WordNet)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#RegulatoryBody -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#RegulatoryBody">
        <rdfs:label>regulatory body</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Organization"/>
        <ru-meta:definition>organization that has the function of issuing regulations or laws</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Reptile -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Reptile">
        <rdfs:label>reptile</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#ResearcherRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#ResearcherRole">
        <rdfs:label>researcher role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OccupationalRole"/>
        <ru-meta:definition>the role a human plays if he / she is involved in research activities</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#RickettsiaCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#RickettsiaCell">
        <rdfs:label>rickettsia cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Prokaryote"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SequenceInformation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SequenceInformation">
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#InformationObject"/>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SiblingRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SiblingRole">
        <rdfs:label>sibling role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilyRole"/>
        <ru-meta:definition>the role an organism plays in relation to another organism that has the same parents</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SignOrSymptomRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SignOrSymptomRole">
        <rdfs:label>sign or symptom role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FindingRole"/>
        <ru-meta:definition>A role that can inhere in states, processes, or even in certain independent continuants (e.g. in a deformity). This a role is ascribed to an entity in a diagnostic process where the symptom is suspected to indicate a second state or process)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SignallingRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SignallingRole">
        <rdfs:label>signalling role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSystemRole"/>
        <ru-meta:definition>The role of a biological entity that participates in a biological signalling process.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SocialAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SocialAction">
        <rdfs:label>social action</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HumanPopulation"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Organization"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>action that targets a population</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SocialBehavior -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SocialBehavior">
        <rdfs:label>social behavior</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Behavior"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Population"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Behaviour of a group of organisms</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SolidValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SolidValueRegion">
        <rdfs:label>solid value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion"/>
        <rdfs:comment>&quot;solid&quot; as the value of a states of matter. E.g. a stone has a quality which has its value located in &quot;solid value region&quot;</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpatialReferenceRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpatialReferenceRole">
        <rdfs:label>spatial reference role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Role"/>
        <ru-meta:definition>The role attributed to a - mainly fiat - part of an object that is the site of some process or the location of some object of interest.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpatialRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpatialRegion">
        <rdfs:label>spatial region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ImmaterialThreeDimensionalPhysicalEntity"/>
        <ru-meta:definition>An independent continuant entity that is neither a bearer of qualities nor inheres in any other entity (snap:SpatialRegion)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpeciesCandidaAlbicansValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpeciesCandidaAlbicansValueRegion">
        <rdfs:label>species candida albicans value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#GenusCandidaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpeciesDrosophilaMelanogasterValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpeciesDrosophilaMelanogasterValueRegion">
        <rdfs:label>species drosophila melanogaster value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#GenusDrosophilaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpeciesEscherichiaColiValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpeciesEscherichiaColiValueRegion">
        <rdfs:label>species escherichia coli value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#GenusEscherichiaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpeciesHomoSapiensValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpeciesHomoSapiensValueRegion">
        <rdfs:label>species homo sapiens value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#GenusHomoValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SpeciesSaccharomycesCerevisiaeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SpeciesSaccharomycesCerevisiaeValueRegion">
        <rdfs:label>species saccharomyces cerevisiae value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#GenusSaccharomycesValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#StateOfMatter -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#StateOfMatter">
        <rdfs:label>state of matter</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ObjectQuality"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>States of matter are the distinct forms that different phases of matter take on.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#StateOfMatterValueRegion">
        <rdfs:label>state of matter value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#ValueRegion"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isProjectionOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#StateOfMatter"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Values that a states of matter can have, e.g. liquid, solid.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#StaticProcessualEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#StaticProcessualEntity">
        <rdfs:label>static processual entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#InformationObject"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject"/>
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TwoDimensionalPhysicalEntity"/>
                        </owl:unionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <owl:priorVersion>State</owl:priorVersion>
        <rdfs:comment>Static condition as a special case of process in which temporal parts are neglected.  </rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Steroid -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Steroid">
        <rdfs:label>steroid</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#LipidMoleculeOrResidue"/>
        <ru-meta:definition>One of a group of polycyclic, 17-carbon-atom, fused-ring compounds occurring both in natural and synthetic forms. Included here are naturally occurring and synthetic steroids, bufanolides, cardanolides, homosteroids, norsteroids, and secosteroids. (UMLS SN)</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity">
        <rdfs:label>structured biological entity</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#PolyMolecularCompositeEntity"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Corresponds to FMA anatomical structure but extends to any kind of orgnaism: Material anatomical entity which is generated by coordinated expression of the organism&apos;s own genes that guide its morphogenesis; has inherent 3D shape; its parts are connected and spatially related to one another in patterns determined by coordinated gene expression. Examples: heart, right ventricle, mitral valve, myocardium, endothelium, lymphocyte, fibroblast, thorax, cardiovascular system, hemoglobin, T cell receptor.
Old name: anatomical structure</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#StructuredNonbiologicalCompound -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#StructuredNonbiologicalCompound">
        <rdfs:label>structured nonbiological compound</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#PolyMolecularCompositeEntity"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>All those things that are not identified by belonging to any biological species
Borderline cases are artifacts that use biological substance (a table, a cloth, a house, a meal ...) A criterion to draw the boundary is whether or not the species affiliation has some structural or functional implication.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SubfamilyDrosophilinaeValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SubfamilyDrosophilinaeValueRegion">
        <rdfs:label>subfamily drosophilinae value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#FamilyDrosophilidaeValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SubjectOfCareRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SubjectOfCareRole">
        <rdfs:label>subject of care role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
        <ru-meta:definition>the role an animal or human plays as receiver of health care</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SubmolecularGroup -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SubmolecularGroup">
        <rdfs:label>submolecular group</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#MonoMolecularEntity"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf rdf:resource="http://purl.org/biotop/biotop.owl#EntireMolecularEntity"/>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isComponentPartOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.org/biotop/biotop.owl#OligoOrPolymer"/>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>A submolecular group or moiety is a group of covalently bound atoms that occurs only as part of a molecule</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SubphylumSaccharomycotinaValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SubphylumSaccharomycotinaValueRegion">
        <rdfs:label>subphylum saccharomycotina value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PhylumAscomycotaValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SubphylumVertebrataValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SubphylumVertebrataValueRegion">
        <rdfs:label>subphylum vertebrata value region</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PhylumChordataValueRegion"/>
        <rdfs:comment>EXAMPLE OF TAXON REGION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#SubstanceInteraction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#SubstanceInteraction">
        <rdfs:label>substance interaction</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Interacting"/>
        <ru-meta:definition>action in which molecular entities interact</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Syncytium -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Syncytium">
        <rdfs:label>syncytium</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Cytoplasm"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CellMembrane"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
        <ru-meta:definition>Fusion of cells </ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#TherapeuticRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#TherapeuticRole">
        <rdfs:label>therapeutic role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
        <ru-meta:definition>1. The role of a continuant participating in a process with an expected positive impact on a dysfunctional biological system.
2. The role of a process with an expected positive impact on a dysfunctional biological system.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Tissue -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Tissue">
        <rdfs:label>tissue</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#PortionOfHeterogenousSolid"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#EntireMolecularEntity"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MulticellularOrganism"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Aggregate of an arbitrary number of congeneric cells (cells with identical specialized characteristics), embedded into an amount of matter (matrix) that work together to perform a specific function.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#TissueProcess -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#TissueProcess">
        <rdfs:label>tissue process</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalProcessualEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasParticipant"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Tissue"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>process occurring in a tissue</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Treating -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Treating">
        <rdfs:label>treating</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:unionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#TreatingCondition"/>
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#TreatingOrganism"/>
                </owl:unionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <ru-meta:definition>action with the intention to produce a positive effect on a biological organism or in which a malfunctioning is relieved or disrupted.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#TreatingCondition -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#TreatingCondition">
        <rdfs:label>treating condition</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:allValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#TherapeuticRole"/>
                    </owl:Restriction>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasPatient"/>
                <owl:allValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isParticipantIn"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#NoncanonicalStaticProcessualEntity"/>
                    </owl:Restriction>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>action with the intention to relieve or disrupt a malfunctioning of a biological entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#TreatingOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#TreatingOrganism">
        <rdfs:label>treating organism</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Affecting"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasAgent"/>
                <owl:allValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#OccupationalRole"/>
                    </owl:Restriction>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasPatient"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>action with the intention to produce a positive effect on a biological organism</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#TwoDimensionalBiologicalEntity -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#TwoDimensionalBiologicalEntity">
        <rdfs:label>two dimensional biological entity</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TwoDimensionalPhysicalEntity"/>
                    <owl:Class>
                        <owl:unionOf rdf:parseType="Collection">
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#properPhysicalPartOf"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBoundaryOf"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSpace"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBoundaryOf"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
                            </owl:Restriction>
                        </owl:unionOf>
                    </owl:Class>
                    <owl:Class>
                        <owl:complementOf>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSpace"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:complementOf>
                    </owl:Class>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBoundaryOf"/>
                        <owl:allValuesFrom>
                            <owl:Class>
                                <owl:unionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSpace"/>
                                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
                                </owl:unionOf>
                            </owl:Class>
                        </owl:allValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>surface or plane in a biological entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#UnicellularOrganism -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#UnicellularOrganism">
        <rdfs:label>unicellular organism</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#LivingOrganism"/>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.org/biotop/biotop.owl#Syncytium"/>
                    </owl:Class>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Cytoplasm"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CellMembrane"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <ru-meta:definition>Organisms that (always or in certain initial stages) consist of a single cell. We conceive organisms in a material sense. Therefore we do not assume any ontological difference between a monocellular organism and the cell it is made of.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#UsingAction -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#UsingAction">
        <rdfs:label>using action</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/btl2.owl#Action"/>
        <ru-meta:definition>action that relates a user with an object he/she uses</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Vertebrate -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Vertebrate">
        <rdfs:label>vertebrate</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#AnimalIncludingHuman"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
                            </owl:Restriction>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:complementOf>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Class>
                        <owl:intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality"/>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubphylumVertebrataValueRegion"/>
                            </owl:Restriction>
                            <owl:Restriction>
                                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#SubphylumVertebrataValueRegion"/>
                            </owl:Restriction>
                        </owl:intersectionOf>
                    </owl:Class>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>one vertebrate</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#VertebratePopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#VertebratePopulation">
        <rdfs:label>vertebrate population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Vertebrate"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#Virus -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#Virus">
        <rdfs:label>virus</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#OrganismByTaxonPartition"/>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
                    </owl:Restriction>
                </owl:complementOf>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:complementOf rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Sub-microscopic agent that requires a host cell to grow and reproduce. Viruses resemble other organisms in that they possess genes, and can evolve in infected cells by natural selection.  We therefore classify viruses as organisms, although there is an open debate.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#VirusPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#VirusPopulation">
        <rdfs:label>virus population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Virus"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Virus"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#VitaminRole -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#VitaminRole">
        <rdfs:label>vitamin role</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#BiologicalSystemRole"/>
        <ru-meta:definition>The role a certain substance can play in an organism. Vitamins are organic compounds that are essential to an organism for metabolic reactions. They are not food. Vitamin does not include essential fatty acids or essential amino acids</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#WaterMolecule -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#WaterMolecule">
        <rdfs:label>water molecule</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#InorganicMolecularEntity"/>
        <ru-meta:definition>A water molecule is composed by one oxygen molecule and two hydrogen molecules</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#WellFormedBiologicalStructure -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#WellFormedBiologicalStructure">
        <rdfs:label>well formed biological structure</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#StructuredBiologicalEntity"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                        <owl:someValuesFrom>
                            <owl:Class>
                                <owl:intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.org/biotop/btl2.owl#Canonicity"/>
                                    <owl:Restriction>
                                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#CanonicalValueRegion"/>
                                    </owl:Restriction>
                                </owl:intersectionOf>
                            </owl:Class>
                        </owl:someValuesFrom>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#YeastCell -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#YeastCell">
        <rdfs:label>yeast cell</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.org/biotop/biotop.owl#Fungus"/>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#isBearerOf"/>
                <owl:someValuesFrom>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#projectsOnto"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#MicroscopicValueRegion"/>
                    </owl:Restriction>
                </owl:someValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#Cytoplasm"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#CellMembrane"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasComponentPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#CellularComponent"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </rdfs:subClassOf>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#hasProperPhysicalPart"/>
                <owl:allValuesFrom>
                    <owl:Class>
                        <owl:complementOf rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
                    </owl:Class>
                </owl:allValuesFrom>
            </owl:Restriction>
        </rdfs:subClassOf>
        <rdfs:comment>Unicellular Fungi.</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/biotop.owl#YeastPopulation -->

    <owl:Class rdf:about="http://purl.org/biotop/biotop.owl#YeastPopulation">
        <rdfs:label>yeast population</rdfs:label>
        <owl:equivalentClass>
            <owl:Class>
                <owl:intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Population"/>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:someValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#YeastCell"/>
                    </owl:Restriction>
                    <owl:Restriction>
                        <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#hasGranularPart"/>
                        <owl:allValuesFrom rdf:resource="http://purl.org/biotop/biotop.owl#YeastCell"/>
                    </owl:Restriction>
                </owl:intersectionOf>
            </owl:Class>
        </owl:equivalentClass>
        <rdfs:comment>EXAMPLE OF POPULATION</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#CanonicalValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#CanonicalValueRegion">
        <rdfs:label>canonical value region</rdfs:label>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion"/>
        <rdfs:comment>abstract region in which the value &quot;canonical&quot; of canonicity is located</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#CellularComponent -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#CellularComponent">
        <rdfs:label>cellular component</rdfs:label>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/biotop.owl#originatesFrom"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Cell"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>Components which only can be formed inside living cells but which may survive their host cell.</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#ImmaterialObject -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#ImmaterialObject">
        <rdfs:label>immaterial object</rdfs:label>
        <owl:priorVersion>immaterial physical entity</owl:priorVersion>
        <ru-meta:definition>Physical spaces that have a threedimensional spatial dimension but no mass.
Old name: immaterial anatomical entity</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#MaterialObject -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#MaterialObject">
        <rdfs:label>material object</rdfs:label>
        <ru-meta:definition>A material object that has exactly one mass and one volume at a time.  Material objects may have Immaterial nonphysical entities as parts (e.g. Heart and Heart Ventricle). </ru-meta:definition>
        <owl:priorVersion>material entity</owl:priorVersion>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#NoncanonicalValueRegion">
        <rdfs:label>noncanonical value region</rdfs:label>
        <rdfs:comment>abstract region in which the value &quot;noncanonical&quot; of canonicity is located</rdfs:comment>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#PointInTime -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#PointInTime">
        <rdfs:label>point in time</rdfs:label>
        <owl:disjointWith rdf:resource="http://purl.org/biotop/btl2.owl#TimeInterval"/>
        <ru-meta:definition>typically the boundary of a time interval</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#Process -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#Process">
        <rdfs:label>process</rdfs:label>
        <ru-meta:definition>Process is in BioTop the generic subsumer of anything that &quot;occurs&quot;. 
Processes can span across time and have temporal parts (i.e. there is no time in which all parts of a process are simultaneously present). 

A special kind of process is the event, which has no temporal extension. It can be regarded as Process Boundary (BFO).


Processes have physical or informational entities as participants.</ru-meta:definition>
        <owl:priorVersion>processual entity</owl:priorVersion>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#ProcessQuality -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#ProcessQuality">
        <rdfs:label>process quality</rdfs:label>
        <rdfs:subClassOf>
            <owl:Restriction>
                <owl:onProperty rdf:resource="http://purl.org/biotop/btl2.owl#inheresIn"/>
                <owl:someValuesFrom rdf:resource="http://purl.org/biotop/btl2.owl#Process"/>
            </owl:Restriction>
        </rdfs:subClassOf>
        <ru-meta:definition>A quality that inheres in some process</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#TaxonQuality -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#TaxonQuality">
        <rdfs:label>taxon quality</rdfs:label>
        <ru-meta:definition>The quality of one or more biological organisms, as well as of parts of organism of partaining to a biological taxon. [steschu20080127]</ru-meta:definition>
    </owl:Class>
    


    <!-- http://purl.org/biotop/btl2.owl#TimeInterval -->

    <owl:Class rdf:about="http://purl.org/biotop/btl2.owl#TimeInterval">
        <rdfs:label>time interval</rdfs:label>
        <ru-meta:definition>the interval between two time points</ru-meta:definition>
    </owl:Class>
    


    <!-- http://www.w3.org/2002/07/owl#Thing -->

    <owl:Class rdf:about="&owl;Thing"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // General axioms
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Eukaryote"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Prokaryote"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Virus"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ImmunologicRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#SignallingRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#VitaminRole"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AdultValueRegion"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#EmbryonicValueRegion"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#JuvenileValueRegion"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BodySystem"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Organ"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#OrganPart"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#MoleculeComplex"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StructuredBiologicalEntity"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#StructuredNonbiologicalCompound"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Electron"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Neutron"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Proton"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#CellMembrane"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#CellNucleus"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Cytoplasm"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#Genome"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#NucleicAcidStructure"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#NucleosideMolecule"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#NucleotideMolecule"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HormoneRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#NeuroreactiveRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ReceptorRole"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#CatalyticRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#IndicatorRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ReagentRole"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ArtefactRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#BiologicalSystemRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#ChemicalRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#FamilyRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HealthRelatedRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#OccupationalRole"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#SpatialReferenceRole"/>
        </owl:members>
    </rdf:Description>
    <rdf:Description>
        <rdf:type rdf:resource="&owl;AllDisjointClasses"/>
        <owl:members rdf:parseType="Collection">
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#AminoAcidOrPeptideMoleculeOrStructure"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#CarbohydrateMoleculeOrResidue"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#FattyAcidMoleculeOrResidue"/>
            <rdf:Description rdf:about="http://purl.org/biotop/biotop.owl#HeterocyclicBaseMoleculeOrResidue"/>
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