@prefix aberowl: <http://aber-owl.net/ontology/> .
@prefix bioportal: <https://bioportal.bioontology.org/ontologies/> .
@prefix bioregistry: <https://bioregistry.io/registry/> .
@prefix bioregistry.metaresource: <https://bioregistry.io/metaregistry/> .
@prefix bioregistry.schema: <https://bioregistry.io/schema/#> .
@prefix dcat: <http://www.w3.org/ns/dcat#> .
@prefix dcterms: <http://purl.org/dc/terms/> .
@prefix doap: <http://usefulinc.com/ns/doap#> .
@prefix foaf: <http://xmlns.com/foaf/0.1/> .
@prefix obo: <http://purl.obolibrary.org/obo/> .
@prefix obofoundry: <https://www.obofoundry.org/ontology/> .
@prefix ols: <https://www.ebi.ac.uk/ols4/ontologies/> .
@prefix ontobee: <http://www.ontobee.org/ontology/> .
@prefix orcid: <https://orcid.org/> .
@prefix rdfs: <http://www.w3.org/2000/01/rdf-schema#> .
@prefix skos: <http://www.w3.org/2004/02/skos/core#> .
@prefix wikidata: <http://www.wikidata.org/entity/> .
@prefix xsd: <http://www.w3.org/2001/XMLSchema#> .

bioregistry.metaresource:aberowl dcterms:hasPart aberowl:TXPO .

bioregistry.metaresource:bioportal dcterms:hasPart bioportal:TXPO .

bioregistry.metaresource:bioregistry dcterms:hasPart bioregistry:txpo .

bioregistry.metaresource:obofoundry dcterms:hasPart obofoundry:txpo .

bioregistry.metaresource:ols dcterms:hasPart ols:txpo .

bioregistry.metaresource:ontobee dcterms:hasPart ontobee:TXPO .

bioregistry.metaresource:wikidata.entity dcterms:hasPart wikidata:Q113014440 .

bioregistry:txpo a bioregistry.schema:0000001 ;
    rdfs:label "Toxic Process Ontology" ;
    dcterms:description """Elucidating the mechanism of toxicity is crucial in drug safety evaluations. TOXic Process Ontology (TXPO) systematizes a wide variety of terms involving toxicity courses and processes. The first version of TXPO focuses on liver toxicity.

The TXPO contains an is-a hierarchy that is organized into three layers: the top layer contains general terms, mostly derived from the Basic Formal Ontology. The intermediate layer contains biomedical terms in OBO foundry from UBERON, Cell Ontology, NCBI Taxon, ChEBI, Gene Ontology, PATO, OGG, INOH, HINO, NCIT, DOID and Relational ontology (RO). The lower layer contains toxicological terms.

In applied work, we have developed a prototype of TOXPILOT, a TOXic Process InterpretabLe knOwledge sysTem. TOXPILOT provides visualization maps of the toxic course, which facilitates capturing the comprehensive picture for understanding toxicity mechanisms. A prototype of TOXPILOT is available: https://toxpilot.nibiohn.go.jp"""^^xsd:string ;
    dcterms:isPartOf bioregistry.metaresource:bioregistry ;
    doap:GitRepository <https://github.com/txpo-ontology/TXPO> ;
    skos:exactMatch aberowl:TXPO,
        ontobee:TXPO,
        wikidata:Q113014440,
        bioportal:TXPO,
        ols:txpo,
        obofoundry:txpo ;
    dcat:keyword "obo",
        "ontology" ;
    foaf:homepage <https://toxpilot.nibiohn.go.jp/> ;
    bioregistry.schema:0000005 "0002066"^^xsd:string ;
    bioregistry.schema:0000006 "http://purl.obolibrary.org/obo/TXPO_$1"^^xsd:string ;
    bioregistry.schema:0000008 "^\\d{7}$"^^xsd:string ;
    bioregistry.schema:0000010 obo:txpo.owl ;
    bioregistry.schema:0000012 false ;
    bioregistry.schema:0000019 orcid:0000-0002-9673-1283 ;
    bioregistry.schema:0000024 "http://purl.obolibrary.org/obo/TXPO_"^^xsd:string ;
    bioregistry.schema:0000027 obo:TXPO_0002066 ;
    bioregistry.schema:0000029 "txpo" .

orcid:0000-0002-9673-1283 rdfs:label "Yuki Yamagata" ;
    foaf:mbox "yuki.yamagata@riken.jp" .

aberowl:TXPO dcterms:isPartOf bioregistry.metaresource:aberowl .

ontobee:TXPO dcterms:isPartOf bioregistry.metaresource:ontobee .

wikidata:Q113014440 dcterms:isPartOf bioregistry.metaresource:wikidata.entity .

bioportal:TXPO dcterms:isPartOf bioregistry.metaresource:bioportal .

ols:txpo dcterms:isPartOf bioregistry.metaresource:ols .

obofoundry:txpo dcterms:isPartOf bioregistry.metaresource:obofoundry .

