appears_in: []
contributor:
  github: samseaver
  name: Sam Seaver
  orcid: 0000-0002-7674-5194
depends_on: []
deprecated: false
description: 'With the growing number of available genomes, the need for an environment
  to support effective comparative analysis increases. The original SEED Project was
  started in 2003 by the [Fellowship for Interpretation of Genomes (FIG)](http://thefig.info/)
  as a largely unfunded open source effort. Argonne National Laboratory and the University
  of Chicago joined the project, and now much of the activity occurs at those two
  institutions (as well as the University of Illinois at Urbana-Champaign, Hope college,
  San Diego State University, the Burnham Institute and a number of other institutions).
  The cooperative effort focuses on the development of the comparative genomics environment
  called the SEED and, more importantly, on the development of curated genomic data.

  This prefix provides identifiers for molecular roles that describe the function
  of one or more proteins in microbes and plants.'
example: Histidinol dehydrogenase (EC 1.1.1.23)
example_extras:
- Archease
- Xylan oligosaccharide ABC transporter, substrate-binding component
github_request_issue: 1340
homepage: https://theseed.org/
keywords: []
license: MIT
mappings: {}
name: The SEED
preferred_prefix: seed.role
prefix: seed.role
providers: []
publications:
- doi: 10.1093/nar/gki866
  pmc: PMC1251668
  pubmed: '16214803'
  title: The Subsystems Approach to Genome Annotation and its Use in the Project to
    Annotate 1000 Genomes
  year: 2005
repository: https://github.com/orgs/TheSEED
reviewer:
  email: b.gyori@northeastern.edu
  github: bgyori
  name: Benjamin M. Gyori
  orcid: 0000-0001-9439-5346
synonyms: []
uri_format: https://pubseed.theseed.org/SubsysEditor.cgi?page=FunctionalRolePage&fr=$1
