appears_in: [] contact: email: anne.morgat@sib.swiss name: Anne Morgat orcid: 0000-0002-1216-2969 depends_on: [] deprecated: false description: ' Rhea is an expert-curated knowledgebase of chemical and transport reactions of biological interest. Enzyme-catalyzed and spontaneously occurring reactions are curated from peer-reviewed literature and represented in a computationally tractable manner by using the ChEBI (Chemical Entities of Biological Interest) ontology to describe reaction participants. Rhea covers the reactions described by the IUBMB Enzyme Nomenclature as well as many additional reactions and can be used for enzyme annotation, genome-scale metabolic modeling and omics-related analyses. Rhea is the standard for enzyme and transporter annotation in UniProtKB.' example: '12345' homepage: https://www.rhea-db.org/ keywords: - biochemistry - life science - reaction - small molecule mappings: biocontext: RHEA edam: '2644' fairsharing: FAIRsharing.pn1sr5 go: RHEA integbio: nbdc02083 miriam: rhea n2t: rhea pathguide: '310' prefixcommons: rhea re3data: r3d100010891 togoid: Rhea name: Rhea, the Annotated Reactions Database namespace_in_lui: false pattern: ^\d{5}$ preferred_prefix: rhea prefix: rhea providers: - code: bio2rdf description: Bio2RDF is an open-source project that uses Semantic Web technologies to build and provide the largest network of Linked Data for the Life Sciences. Bio2RDF defines a set of simple conventions to create RDF(S) compatible Linked Data from a diverse set of heterogeneously formatted sources obtained from multiple data providers. homepage: https://bio2rdf.org name: Bio2RDF uri_format: http://bio2rdf.org/rhea:$1 publications: - doi: 10.1093/nar/gkab1016 pmc: PMC8728268 pubmed: '34755880' title: Rhea, the reaction knowledgebase in 2022 year: 2022 - doi: 10.1093/bioinformatics/btz817 pmc: PMC7162351 pubmed: '31688925' title: Enzyme annotation in UniProtKB using Rhea year: 2020 - doi: 10.1093/nar/gky876 pmc: PMC6324061 pubmed: '30272209' title: 'Updates in Rhea: SPARQLing biochemical reaction data' year: 2019 - doi: 10.1093/nar/gkw990 pmc: PMC5210663 pubmed: '27789701' title: Updates in Rhea - an expert curated resource of biochemical reactions year: 2016 - doi: 10.1093/nar/gku961 pmc: PMC4384025 pubmed: '25332395' title: Updates in Rhea--a manually curated resource of biochemical reactions year: 2014 - doi: 10.1093/nar/gkr1126 pmc: PMC3245052 pubmed: '22135291' title: Rhea--a manually curated resource of biochemical reactions year: 2011 synonyms: - RHEA twitter: rhea_db uri_format: https://www.rhea-db.org/rhea/$1