appears_in: []
contact:
  email: jfernand@um.es
  github: jesualdotomasfernandezbreis
  name: Jesualdo Tomás Fernández-Breis
  orcid: 0000-0002-7558-2880
depends_on: []
deprecated: false
description: 'The need of a common ontology for describing orthology information in
  biological research communities has led to the creation of the Orthology Ontology
  (ORTH). ORTH ontology is designed to describe sequence homology data available in
  multiple orthology databases on the Web (e.g.: OMA, OrthoDB, HieranoiDB, and etc.).
  By sequence homology data, we mostly mean gene region, gene and protein centric
  orthology, paralogy, and xenology information. Depending on the database, the homology
  information is structured in different ways. ORTH ontology accommodates these disparate
  data structures namely Hierarchical Orthologous Group (HOG), cluster of homologous
  sequences and homologous-pairwise relations between sequences. In addition to the
  specific ORTH terms, this specification includes terms of the imported ontologies
  (e.g. Semanticscience Integrated Ontology, SIO) which are pertinents to represent
  the information from various orthology databases in a homogeneous way.'
download_owl: https://github.com/qfo/OrthologyOntology/raw/master/orthOntology_RC_v2_A.owl
example: HomologyRelation
example_extras: []
homepage: https://github.com/qfo/OrthologyOntology
keywords:
- comparative genomics
- gene
- homologous
- ontology
- orthologous
- paralogous
- protein
- sequence
mappings:
  aberowl: ORTH
  bioportal: ORTH
  fairsharing: FAIRsharing.4877h0
  ols: orth
name: Orthology Ontology
preferred_prefix: orth
prefix: orth
providers: []
publications:
- doi: 10.1186/s13326-016-0077-x
  pmc: PMC4893294
  pubmed: '27259657'
  title: 'The Orthology Ontology: development and applications'
  year: 2016
repository: https://github.com/qfo/OrthologyOntology
synonyms: []
uri_format: http://purl.org/net/orth#$1
version: '2.0'
