biocontext: is_identifiers: true is_obo: false prefix: HPA uri_format: http://identifiers.org/hpa/$1 fairsharing: abbreviation: HPA contact: email: mathias.uhlen@scilifelab.se name: Mathias Uhlen orcid: 0000-0002-4858-8056 description: 'The Human Protein Atlas (HPA) portal is a publicly available database with millions of high-resolution images showing the spatial distribution of proteins in a number of different wild-type tissues, cancer types and human cell lines. The goal of the HPA is to map all the human proteins in cells, tissues and organs using an integration of various omics technologies, including antibody-based imaging, mass spectrometry-based proteomics, transcriptomics and systems biology. The HPA is composed of six parts: the Tissue Atlas, the Single Cell Type Atlas, the Pathology Atlas, the Blood Atlas, the Brain Atlas, and the Cell Atlas.' homepage: https://www.proteinatlas.org/ license: CC BY-SA 3.0 name: The Human Protein Atlas prefix: FAIRsharing.j0t0pe publications: - doi: 10.1074/mcp.R800013-MCP200 pubmed_id: 18669619 title: A genecentric Human Protein Atlas for expression profiles based on antibodies. - doi: 10.1002/path.2440 pubmed_id: 18853439 title: The Human Protein Atlas--a tool for pathology. - doi: 10.15252/msb.20155865 pubmed_id: 27044256 title: Transcriptomics resources of human tissues and organs. - doi: 10.1126/science.1260419 pubmed_id: 25613900 title: Tissue-based map of the human proteome. - doi: 10.1126/science.aan2507 pubmed_id: 28818916 title: A pathology atlas of the human cancer transcriptome - doi: 10.1038/nbt1210-1248 pubmed_id: 21139605 title: Towards a knowledge-based Human Protein Atlas. - doi: 10.1074/mcp.M500279-MCP200 pubmed_id: 16127175 title: A human protein atlas for normal and cancer tissues based on antibody proteomics. - doi: eaal3321 pubmed_id: 28495876 title: A subcellular map of the human proteome. subjects: - Proteomics - Transcriptomics - Biomedical Science - Systems Biology twitter: ProteinAtlas go: homepage: http://www.proteinatlas.org/ name: Human Protein Atlas tissue profile information prefix: HPA uri_format: http://www.proteinatlas.org/tissue_profile.php?antibody_id=$1 mappings: biocontext: HPA fairsharing: FAIRsharing.j0t0pe go: HPA miriam: hpa n2t: hpa prefixcommons: hpa re3data: r3d100010931 uniprot: DB-0046 miriam: deprecated: false description: The Human Protein Atlas (HPA) is a publicly available database with high-resolution images showing the spatial distribution of proteins in different normal and cancer human cell lines. Primary access to this collection is through Ensembl Gene identifiers. homepage: http://www.proteinatlas.org/ id: '00000336' name: HPA namespaceEmbeddedInLui: false pattern: ^ENSG\d{11}$ prefix: hpa sampleId: ENSG00000026508 uri_format: http://www.proteinatlas.org/$1 n2t: description: The Human Protein Atlas (HPA) is a publicly available database with high-resolution images showing the spatial distribution of proteins in different normal and cancer human cell lines. Primary access to this collection is through Ensembl Gene identifiers. example: ENSG00000026508 homepage: http://www.proteinatlas.org/ name: Human Protein Atlas at AlbaNova University namespaceEmbeddedInLui: false pattern: ^ENSG\d{11}$ prefix: hpa uri_format: http://www.proteinatlas.org/$1 prefixcommons: description: The Human Protein Atlas (HPA) portal is a publicly available database with millions of high-resolution images showing the spatial distribution of proteins in 48 different normal tissues and 20 different cancer types as well as 47 different human cell lines. example: ENSG00000026508 homepage: http://www.proteinatlas.org/ keywords: - protein - structure name: Human Protein Atlas pattern: ^ENSG\d{11}$ prefix: hpa pubmed_ids: - '18669619' uri_format: http://www.proteinatlas.org/gene_info.php?ensembl_gene_id=$1 publications: - doi: 10.1126/science.aan2507 pubmed: '28818916' title: A pathology atlas of the human cancer transcriptome. year: 2017 - doi: 10.1126/science.aal3321 pubmed: '28495876' title: A subcellular map of the human proteome. year: 2017 - doi: 10.15252/msb.20155865 pmc: PMC4848759 pubmed: '27044256' title: "Transcriptomics resources of human tissues and\_organs." year: 2016 - doi: 10.1126/science.1260419 pubmed: '25613900' title: Proteomics. Tissue-based map of the human proteome. year: 2015 - doi: 10.1038/nbt1210-1248 pubmed: '21139605' title: Towards a knowledge-based Human Protein Atlas. year: 2010 - doi: 10.1002/path.2440 pubmed: '18853439' title: The Human Protein Atlas--a tool for pathology. year: 2008 - doi: 10.1074/mcp.r800013-mcp200 pubmed: '18669619' title: A genecentric Human Protein Atlas for expression profiles based on antibodies. year: 2008 - doi: 10.1074/mcp.m500279-mcp200 pubmed: '16127175' title: A human protein atlas for normal and cancer tissues based on antibody proteomics. year: 2005 - doi: 10.1074/mcp.r800013-mcp200 pubmed: '18669619' title: A genecentric Human Protein Atlas for expression profiles based on antibodies. - doi: 10.1002/path.2440 pubmed: '18853439' title: The Human Protein Atlas--a tool for pathology. - doi: 10.15252/msb.20155865 pubmed: '27044256' title: Transcriptomics resources of human tissues and organs. - doi: 10.1126/science.1260419 pubmed: '25613900' title: Tissue-based map of the human proteome. - doi: 10.1126/science.aan2507 pubmed: '28818916' title: A pathology atlas of the human cancer transcriptome - doi: 10.1038/nbt1210-1248 pubmed: '21139605' title: Towards a knowledge-based Human Protein Atlas. - doi: 10.1074/mcp.m500279-mcp200 pubmed: '16127175' title: A human protein atlas for normal and cancer tissues based on antibody proteomics. - doi: eaal3321 pubmed: '28495876' title: A subcellular map of the human proteome. - pubmed: '18669619' - doi: 10.1126/science.1260419 pubmed: '25613900' - doi: 10.1074/mcp.r800013-mcp200 pubmed: '18669619' title: A genecentric Human Protein Atlas for expression profiles based on antibodies. - doi: 10.1002/path.2440 pubmed: '18853439' title: The Human Protein Atlas--a tool for pathology. - doi: 10.15252/msb.20155865 pubmed: '27044256' title: Transcriptomics resources of human tissues and organs. - doi: 10.1126/science.1260419 pubmed: '25613900' title: Tissue-based map of the human proteome. - doi: 10.1126/science.aan2507 pubmed: '28818916' title: A pathology atlas of the human cancer transcriptome - doi: 10.1038/nbt1210-1248 pubmed: '21139605' title: Towards a knowledge-based Human Protein Atlas. - doi: 10.1074/mcp.m500279-mcp200 pubmed: '16127175' title: A human protein atlas for normal and cancer tissues based on antibody proteomics. - doi: eaal3321 pubmed: '28495876' title: A subcellular map of the human proteome. - pubmed: '18669619' - doi: 10.1126/science.1260419 pubmed: '25613900' - doi: 10.1074/mcp.r800013-mcp200 pubmed: '18669619' title: A genecentric Human Protein Atlas for expression profiles based on antibodies. - doi: 10.1002/path.2440 pubmed: '18853439' title: The Human Protein Atlas--a tool for pathology. - doi: 10.15252/msb.20155865 pubmed: '27044256' title: Transcriptomics resources of human tissues and organs. - doi: 10.1126/science.1260419 pubmed: '25613900' title: Tissue-based map of the human proteome. - doi: 10.1126/science.aan2507 pubmed: '28818916' title: A pathology atlas of the human cancer transcriptome - doi: 10.1038/nbt1210-1248 pubmed: '21139605' title: Towards a knowledge-based Human Protein Atlas. - doi: 10.1074/mcp.m500279-mcp200 pubmed: '16127175' title: A human protein atlas for normal and cancer tissues based on antibody proteomics. - doi: eaal3321 pubmed: '28495876' title: A subcellular map of the human proteome. - pubmed: '18669619' - doi: 10.1126/science.1260419 pubmed: '25613900' - doi: 10.1074/mcp.r800013-mcp200 pubmed: '18669619' title: A genecentric Human Protein Atlas for expression profiles based on antibodies. - doi: 10.1002/path.2440 pubmed: '18853439' title: The Human Protein Atlas--a tool for pathology. - doi: 10.15252/msb.20155865 pubmed: '27044256' title: Transcriptomics resources of human tissues and organs. - doi: 10.1126/science.1260419 pubmed: '25613900' title: Tissue-based map of the human proteome. - doi: 10.1126/science.aan2507 pubmed: '28818916' title: A pathology atlas of the human cancer transcriptome - doi: 10.1038/nbt1210-1248 pubmed: '21139605' title: Towards a knowledge-based Human Protein Atlas. - doi: 10.1074/mcp.m500279-mcp200 pubmed: '16127175' title: A human protein atlas for normal and cancer tissues based on antibody proteomics. - doi: eaal3321 pubmed: '28495876' title: A subcellular map of the human proteome. - pubmed: '18669619' - doi: 10.1126/science.1260419 pubmed: '25613900' re3data: description: The Swedish Human Protein Atlas project has been set up to allow for a systematic exploration of the human proteome using Antibody-Based Proteomics. This is accomplished by combining high-throughput generation of affinity-purified antibodies with protein profiling in a multitude of tissues and cells assembled in tissue microarrays. Confocal microscopy analysis using human cell lines is performed for more detailed protein localization. The program hosts the Human Protein Atlas portal with expression profiles of human proteins in tissues and cells. The main objective of the resource centre is to produce specific antibodies to human target proteins using a high-throughput production method involving the cloning and protein expression of Protein Epitope Signature Tags (PrESTs). After purification, the antibodies are used to study expression profiles in cells and tissues and for functional analysis of the corresponding proteins in a wide range of platforms. homepage: https://www.proteinatlas.org/ name: The Human Protein Atlas prefix: r3d100010931 synonyms: - HPA xrefs: fairsharing: FAIRsharing.j0t0pe miriam: '00000336' nif: 0000-00204 omics: 03913 scr: '006710' uniprot: abbreviation: HPA category: Organism-specific databases homepage: https://www.proteinatlas.org/ name: Human Protein Atlas prefix: DB-0046 publications: - doi: 10.1126/science.1260419 pubmed: '25613900' uri_format: https://www.proteinatlas.org/$1