appears_in: []
contact:
  email: flicek@ebi.ac.uk
  name: Paul Flicek
  orcid: 0000-0002-3897-7955
depends_on: []
deprecated: false
description: Ensembl is a joint project between EMBL - EBI and the Sanger Institute  to
  develop a software system which produces and maintains automatic annotation on selected
  eukaryotic genomes. This collections also references outgroup organisms.
example: ENSG00000139618
example_extras:
- ENSG00000049246.14
- ENSG00000109819.9
- ENSG00000132326.12
- ENSG00000179094.16
- ENST00000264867.7
homepage: https://www.ensembl.org/
keywords:
- biomedical science
- comparative genomics
- genome
- genomics
logo: https://useast.ensembl.org/img/ebang-400dpi.png
mappings:
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  edam: '2610'
  fairsharing: FAIRsharing.fx0mw7
  go: ENSEMBL
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  miriam: ensembl
  n2t: ensembl
  ncbi: ENSEMBL
  prefixcommons: ensembl
  re3data: r3d100010228
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  wikidata: P594
mastodon: ensembl@genomic.social
name: Ensembl Gene
namespace_in_lui: false
pattern: ^((ENS[FPTG]\d{11}(\.\d+)?)|(FB\w{2}\d{7})|(Y[A-Z]{2}\d{3}[a-zA-Z](\-[A-Z])?)|([A-Z_a-z0-9]+(\.)?(t)?(\d+)?([a-z])?))$
preferred_prefix: ensembl
prefix: ensembl
providers:
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  description: Ensembl US East mirror
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  name: Ensembl US East mirror
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  description: Ensembl Asia mirror
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  description: Gene expression in various tissues
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  name: Bgee
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  description: Bio2RDF is an open-source project that uses Semantic Web technologies
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  name: Bio2RDF
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  name: CilioGenics
  uri_format: https://ciliogenics.com/?page=General%20info&query=$1
- code: digger
  description: Digger integrates protein-protein interactions and domain-domain interactions
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  homepage: https://exbio.wzw.tum.de/digger/
  name: Domain Interaction Graph Guided Explorer
  publications:
  - doi: 10.1093/nar/gkaf384
    pmc: PMC12230681
    pubmed: '40337913'
    title: 'DIGGER 2.0: digging into the functional impact of differential splicing
      on human and mouse disorders'
    year: 2025
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- code: gnomad
  description: The Genome Aggregation Database (gnomAD) is a resource developed by
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  homepage: https://gnomad.broadinstitute.org
  name: Genome Aggregation database
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- code: opentargets.genetics
  description: Open Targets Genetics is a comprehensive tool highlighting variant-centric
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    at trait-associated loci and identification of potential drug targets.
  homepage: https://genetics.opentargets.org
  name: OpenTargets Genetics
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publications:
- doi: 10.1093/nar/gkaf384
  pmc: PMC12230681
  pubmed: '40337913'
  title: 'DIGGER 2.0: digging into the functional impact of differential splicing
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  year: 2025
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  title: Ensembl 2022
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  pubmed: '31691826'
  title: Ensembl 2020
  year: 2020
- doi: 10.1093/nar/gky1113
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  pubmed: '30407521'
  title: Ensembl 2019
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  pubmed: '27899575'
  title: Ensembl 2017
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- doi: 10.1093/database/baw093
  pmc: PMC4919035
  pubmed: '27337980'
  title: The Ensembl gene annotation system
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- doi: 10.1186/s13059-016-0974-4
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  pubmed: '27268795'
  title: The Ensembl Variant Effect Predictor
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  pubmed: '27141089'
  title: Ensembl comparative genomics resources
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  pubmed: '26980512'
  title: ncRNA orthologies in the vertebrate lineage
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- doi: 10.1093/database/bav096
  pmc: PMC4761110
  pubmed: '26896847'
  title: Ensembl comparative genomics resources
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  pubmed: '26888907'
  title: Ensembl regulation resources
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- doi: 10.1093/nar/gkv1157
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  pubmed: '26687719'
  title: Ensembl 2016
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- doi: 10.1186/s13059-015-0621-5
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  pubmed: '25887522'
  title: The ensembl regulatory build
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  title: Ensembl 2015
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  title: 'The Ensembl REST API: Ensembl Data for Any Language'
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- doi: 10.1093/bioinformatics/btt737
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  pubmed: '24363377'
  title: 'WiggleTools: parallel processing of large collections of genome-wide datasets
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  pubmed: '24316576'
  title: Ensembl 2014
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  title: Ensembl 2013
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  title: 'GENCODE: the reference human genome annotation for The ENCODE Project'
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- doi: 10.1101/gr.137901.112
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  pubmed: '22798491'
  title: Incorporating RNA-seq data into the zebrafish Ensembl genebuild
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- doi: 10.1093/nar/gkr991
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  pubmed: '22086963'
  title: Ensembl 2012
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  title: 'Ensembl BioMarts: a hub for data retrieval across taxonomic space'
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- doi: 10.1002/0471142905.hg0611s69
  pmc: PMC3099348
  pubmed: '21400687'
  title: Disease and phenotype data at Ensembl
  year: 2011
- doi: 10.1093/nar/gkq1064
  pmc: PMC3013672
  pubmed: '21045057'
  title: Ensembl 2011
  year: 2010
- doi: 10.1093/bioinformatics/btq330
  pmc: PMC2916720
  pubmed: '20562413'
  title: Deriving the consequences of genomic variants with the Ensembl API and SNP
    Effect Predictor
  year: 2010
- doi: 10.1186/1471-2105-11-240
  pmc: PMC2885371
  pubmed: '20459813'
  title: 'eHive: an artificial intelligence workflow system for genomic analysis'
  year: 2010
- doi: 10.1186/1471-2105-11-238
  pmc: PMC2882931
  pubmed: '20459810'
  title: A database and API for variation, dense genotyping and resequencing data
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- doi: 10.1186/1471-2164-11-295
  pmc: PMC2894802
  pubmed: '20459808'
  title: 'Touring Ensembl: a practical guide to genome browsing'
  year: 2010
- doi: 10.1186/1471-2164-11-293
  pmc: PMC2894800
  pubmed: '20459805'
  title: Ensembl variation resources
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- doi: 10.1093/nar/gkp972
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  pubmed: '19906699'
  title: Ensembl's 10th year
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  pubmed: '19033362'
  title: Ensembl 2009
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  title: 'EnsemblCompara GeneTrees: Complete, duplication-aware phylogenetic trees
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  pubmed: '18849525'
  title: Genome-wide nucleotide-level mammalian ancestor reconstruction
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- doi: 10.1093/nar/gkm988
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  pubmed: '18000006'
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  title: 'Genome browsing with Ensembl: a practical overview'
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  title: Ensembl 2007
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  title: Ensembl 2006
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  title: Ensembl 2005
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  title: Genome information resources - developments at Ensembl
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  pubmed: '15123595'
  title: 'ESTGenes: alternative splicing from ESTs in Ensembl'
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  title: The Ensembl computing architecture
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  title: 'The Ensembl Web site: mechanics of a genome browser'
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  title: The Ensembl automatic gene annotation system
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  title: The Ensembl analysis pipeline
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  title: The Ensembl core software libraries
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- doi: 10.1093/nar/gkg083
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  title: 'Ensembl 2002: accommodating comparative genomics'
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  pubmed: '11752248'
  title: The Ensembl genome database project
  year: 2002
- doi: doi:10.1093/nar/gku1010
  title: Ensembl 2015
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synonyms:
- Ensembl
twitter: ensembl
uri_format: https://www.ensembl.org/id/$1
