appears_in: []
comment: The Nomenclature Committee website does not yet contain an official policy
  regarding the use of dashes in the hierarchical categorization of enzymes, so the
  Bioregistry's regular expression is permissive and accepts both EC identifiers with
  dashes (e.g. <code>2.3.-.-</code>) and without dashes (e.g., <code>2.3</code>).
  This means you may have to do post-processing of EC identifiers in data integration
  scenarios.
contact:
  email: kristian.axelsen@sib.swiss
  github: kaxelsen
  name: Kristian Axelsen
  orcid: 0000-0003-3889-2879
depends_on: []
deprecated: false
description: 'The Enzyme Nomenclature (also known as the Enzyme Commission Code) is
  a species-agnostic controlled vocabulary for specific enzymes and an associated
  hierarchical classification into 7 main categories.


  The Enzyme Nomenclature is maintained by the [Nomenclature Committee](https://iubmb.org/about/committees/nomenclature-committee/)
  of the International Union of Biochemistry and Molecular Biology (IUBMB). A detailed
  history of the nomenclature since the 1950s can be found [here](https://iubmb.qmul.ac.uk/enzyme/history.html).


  There are few notable resources providing access to the Enzyme Nomenclature:


  <table class="table table-striped"><thead><tr><th>Website</th><th>Homepage</td><th>Notes</td></tr></thead><tbody><tr><td>ExplorEnz</td><td><a
  href="https://www.enzyme-database.org">https://www.enzyme-database.org</a></td><td>This
  is the resource officially recommended by IUBMB</td></tr><tr><td>IUBMB (via by Queen
  Mary)</td><td><a href="https://iubmb.qmul.ac.uk/enzyme">https://iubmb.qmul.ac.uk/enzyme</a></td><td>This
  is a web-based version of the <a href="https://archive.org/details/enzymenomenclatu0000inte_d6c2">1992
  publication</a>.</td></tr><tr><td>IntEnz</td><td><a href="https://www.ebi.ac.uk/intenz">https://www.ebi.ac.uk/intenz</a></td><td>Shutdown
  in 2024</td></tr><tr><td>ExPaSy</td><td><a href="https://enzyme.expasy.org">https://enzyme.expasy.org</a></td></tr><tr><td>EnzymePortal</td><td><a
  href="https://www.ebi.ac.uk/enzymeportal">https://www.ebi.ac.uk/enzymeportal</a></td><td></td></tr></tbody></table>'
download_json: https://w3id.org/biopragmatics/resources/ec/ec.json
download_obo: https://w3id.org/biopragmatics/resources/ec/ec.obo
download_owl: https://w3id.org/biopragmatics/resources/ec/ec.owl
example: 1.1.1.1
example_decoys:
- '100'
- '2.'
- 2.n1
- 2.3.
- 2.3.n1
- 2.3.1.
- 2.3.1.n
- 2.3.4.1.
- 2.-.-
- 2.-
- 2.3.4.1.-
example_extras:
- '2'
- 2.-.-.-
- '2.3'
- 2.3.-.-
- 2.3.1
- 2.3.1.-
- 2.3.1.n12
- 3.1.26.n2
- 3.4.24.B15
homepage: https://www.enzyme-database.org/
keywords:
- biochemistry
- biopax
- centrally registered identifier
- classification
- enzyme
- enzyme and pathway databases
- enzyme commission number
- enzymology
- function
- ontology
- ontology/terminology/nomenclature
- protein
- repository
- rna
license: CC-BY-4.0
logo: https://www.enzyme-database.org/images/banner_5.gif
mappings:
  bartoc: '671'
  biocontext: EC-CODE
  edam: '1011'
  fairsharing: FAIRsharing.rfLD2u
  go: EC
  integbio: nbdc00508
  miriam: ec-code
  n2t: ec-code
  ols: ec
  pathguide: '106'
  prefixcommons: intenz
  re3data: r3d100010803
  togoid: Ec
  uniprot: DB-0024
  wikidata: P591
  wikidata.entity: Q741108
name: Enzyme Nomenclature
namespace_in_lui: false
owners:
- name: International Union of Biochemistry and Molecular Biology
  ror: 00910ay07
pattern: ^\d{1,2}(((\.\d{1,3}){1,3})|(\.\d+){2}\.[nB]\d{1,3}|\.-\.-\.-|\.\d{1,3}\.-\.-|\.\d{1,3}\.\d{1,3}\.-)?$
preferred_prefix: EC
prefix: ec
providers:
- code: ''
  description: KEGG Ligand Database for Enzyme Nomenclature
  homepage: https://www.genome.jp/dbget-bin/www_bfind?enzyme
  name: KEGG Ligand Database for Enzyme Nomenclature
  uri_format: https://www.genome.jp/dbget-bin/www_bget?ec:$1
- code: bio2rdf
  description: Bio2RDF is an open-source project that uses Semantic Web technologies
    to build and provide the largest network of Linked Data for the Life Sciences.
    Bio2RDF defines a set of simple conventions to create RDF(S) compatible Linked
    Data from a diverse set of heterogeneously formatted sources obtained from multiple
    data providers.
  homepage: https://bio2rdf.org
  name: Bio2RDF
  uri_format: http://bio2rdf.org/intenz:$1
- code: enzymeportal
  description: ' Enzyme Portal integrates publicly available information about enzymes,
    such as reaction mechanism, small-molecule chemistry, biochemical pathways and
    drug compounds.'
  homepage: https://www.ebi.ac.uk/enzymeportal
  name: EnzymePortal
  publications:
  - doi: 10.1093/protein/gzx008
    pmc: PMC5421622
    pubmed: '28158609'
    title: 'An update on the Enzyme Portal: an integrative approach for exploring
      enzyme knowledge'
    year: 2017
  uri_format: https://www.ebi.ac.uk/enzymeportal/ec/$1
- code: expasy
  description: Enzyme nomenclature database, ExPASy (Expert Protein Analysis System)
  homepage: https://enzyme.expasy.org/
  name: Enzyme nomenclature database, ExPASy (Expert Protein Analysis System)
  uri_format: https://enzyme.expasy.org/EC/$1
publications:
- doi: 10.1093/protein/gzx008
  pmc: PMC5421622
  pubmed: '28158609'
  title: 'An update on the Enzyme Portal: an integrative approach for exploring enzyme
    knowledge'
  year: 2017
- pubmed: '14681451'
- doi: 10.1093/nar/28.1.304
  pmc: PMC102465
  pubmed: '10592255'
  title: The ENZYME database in 2000
  year: 2000
rdf_uri_format: https://purl.expasy.org/enzyme/EC/$1
references:
- https://github.com/biopragmatics/bioregistry/issues/681
- https://github.com/biopragmatics/bioregistry/pull/1611
synonyms:
- EC
- EC number
- EC-CODE
- ECCODE
- EC_CODE
- ec-code
- eccode
- intenz
uri_format: https://www.enzyme-database.org/query.php?ec=$1
