{"prefix":"chembl.mechanism","name":"ChEMBL mechanism","description":"This controlled vocabulary contains terms to describe the mechanism of action for a chemical-target interaction. The terms can be retrieved from ACTION_TYPE table in ChEMBL's SQL dump and are used to annotate the DRUG_MECHANISM table. Because these aren't really identifiers, they are transformed by lowercasing and replacing spaces with dashes to form 'identifiers'. The pattern in the Bioregistry record contains an enumeration of the 33 allowed values as of ChEMBL v35.","pattern":"^activator|agonist|allosteric-antagonist|antagonist|antisense-inhibitor|binding-agent|blocker|chelating-agent|cross-linking-agent|degrader|disrupting-agent|exogenous-gene|exogenous-protein|hydrolytic-enzyme|inhibitor|inverse-agonist|methylating-agent|modulator|negative-allosteric-modulator|negative-modulator|opener|other|oxidative-enzyme|partial-agonist|positive-allosteric-modulator|positive-modulator|proteolytic-enzyme|reducing-agent|releasing-agent|rnai-inhibitor|sequestering-agent|stabiliser|substrate|vaccine-antigen$","providers":[],"homepage":"https://www.ebi.ac.uk/chembl","contact":{"name":"David Mendez Lopez","orcid":"0000-0002-0294-5484","email":"dmendez@ebi.ac.uk","github":"nclopezo"},"example":"activator","example_extras":["cross-linking-agent","negative-allosteric-modulator"],"license":"CC-BY-SA-3.0","part_of":"chembl","deprecated":false,"mappings":{},"synonyms":[],"keywords":[],"publications":[],"appears_in":[],"depends_on":[],"namespace_in_lui":false,"contributor":{"name":"Charles Tapley Hoyt","orcid":"0000-0003-4423-4370","email":"cthoyt@gmail.com","github":"cthoyt"},"preferred_prefix":"chembl.mechanism","logo":"https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEg5LCdi4mEW56jpmM0YDjEwLtGUUy2F9I7m02I9hygI0OPugnZKlTrAgfBtug5yJS5RbpCXifID0pzA5Wxdc6un1UjCCtOJcvlkeoAFgzQspvplZcstYNwx8lBtvlYY8WJ-kLj-I891VIAO/s1600/Screenshot+2018-12-20+at+10.30.09.png"}