Reactome | IFNA [extracellular region]

IFNA [extracellular region]

Stable Identifier

R-HSA-909688

Type

Set [DefinedSet]

Species

Homo sapiens

Compartment

extracellular region

Synonyms

interferon alpha subtypes, interferon alpha

Locations in the PathwayBrowser

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Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
      - RSV-host interactions (Homo sapiens)
        
        Evasion by RSV of host interferon responses (Homo sapiens)
        
        Recruitment of STAT2 to p-IFNAR1 (Homo sapiens)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2 [plasma membrane] (Homo sapiens)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2 [plasma membrane] (Homo sapiens)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
        
        IFNA [extracellular region] (Homo sapiens)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:STAT2 [plasma membrane] (Homo sapiens)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
        
        IFNA [extracellular region] (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
        
        Phosphorylation of STAT1 (Homo sapiens)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2 [plasma membrane] (Homo sapiens)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
        
        IFNA [extracellular region] (Homo sapiens)
        
        IFNA/B:IFNAR2:p-JAK1:STAT2:p-IFNAR1:p-TYK2:p-STAT2:p-STAT1 [plasma membrane] (Homo sapiens)
        
        IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)
        
        IFNA [extracellular region] (Homo sapiens)

Literature References

PubMed ID	Title	Journal	Year
9425112	Identification of nine interferon-alpha subtypes produced by Sendai virus-induced human peripheral blood leucocytes Kalkkinen, N, Nyman, TA, Parkkinen, J, Tölö, H	Biochem J	1998

Participants

members

Participates

as a member of

IFN alpha/beta (IFNA/B) [extracellular region] (Homo sapiens)

Inferred To

IFNA [extracellular region] (Bos taurus)

IFNA [extracellular region] (Canis familiaris)

IFNA [extracellular region] (Danio rerio)

IFNA [extracellular region] (Gallus gallus)

IFNA [extracellular region] (Mus musculus)

IFNA [extracellular region] (Rattus norvegicus)

IFNA [extracellular region] (Sus scrofa)

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