AmiGO 2: Term Details for "AMPA glutamate receptor complex" (GO:0032281)

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Term Information

Accession: GO:0032281
Name: AMPA glutamate receptor complex
Ontology: cellular_component
Synonyms: AMPA-selective glutamate receptor complex, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, AMPA receptor
Alternate IDs: None
Definition: An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. Source: GOC:ef
Comment: None
History: See term history for GO:0032281 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to AMPA glutamate receptor complex (excluding "regulates").; Link to all direct and indirect annotations to AMPA glutamate receptor complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for AMPA glutamate receptor complex (excluding "regulates").

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For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
CARO:0000003 connected anatomical structure
GO:0051179 localization
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0110165 cellular anatomical structure
GO:0009987 cellular process
GO:0005575 cellular_component
GO:0015267 channel activity
GO:0051234 establishment of localization
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0006810 transport
GO:0007154 cell communication
GO:0071944 cell periphery
GO:0051716 cellular response to stimulus
GO:0022836 gated channel activity
GO:0022834 ligand-gated channel activity
GO:0016020 membrane
GO:0003674 molecular_function
GO:0005216 monoatomic ion channel activity
GO:0006811 monoatomic ion transport
GO:0015849 organic acid transport
GO:0015711 organic anion transport
GO:0050794 regulation of cellular process
GO:0007165 signal transduction
GO:0023052 signaling
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0006865 amino acid transport
GO:0046942 carboxylic acid transport
GO:0007166 cell surface receptor signaling pathway
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0098796 membrane protein complex
GO:0060089 molecular transducer activity
GO:0034220 monoatomic ion transmembrane transport
GO:0030594 neurotransmitter receptor activity
GO:1903825 organic acid transmembrane transport
GO:0022803 passive transmembrane transporter activity
GO:0005886 plasma membrane
GO:0032991 protein-containing complex
GO:0038023 signaling receptor activity
GO:0005215 transporter activity
GO:0003333 amino acid transmembrane transport
GO:1905039 carboxylic acid transmembrane transport
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0007215 glutamate receptor signaling pathway
GO:1990806 ligand-gated ion channel signaling pathway
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0005342 organic acid transmembrane transporter activity
GO:0008514 organic anion transmembrane transporter activity
GO:0098797 plasma membrane protein complex
GO:0043235 receptor complex
GO:0004888 transmembrane signaling receptor activity
GO:0022835 transmitter-gated channel activity
GO:1990351 transporter complex
GO:0015171 amino acid transmembrane transporter activity
GO:0046943 carboxylic acid transmembrane transporter activity
GO:0008066 glutamate receptor activity
GO:0015318 inorganic molecular entity transmembrane transporter activity
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0098802 plasma membrane signaling receptor complex
GO:1902495 transmembrane transporter complex
GO:0022824 transmitter-gated monoatomic ion channel activity
GO:0004970 glutamate-gated receptor activity
GO:0022890 inorganic cation transmembrane transporter activity
GO:0034702 monoatomic ion channel complex
GO:0098878 neurotransmitter receptor complex
GO:0004971 AMPA glutamate receptor activity
GO:0008328 ionotropic glutamate receptor complex
GO:0032281 AMPA glutamate receptor complex

Parents of AMPA glutamate receptor complex (GO:0032281)

subject	relation	object
AMPA glutamate receptor complex	RO:0002162	Metazoa (NCBITaxon:33208)
AMPA glutamate receptor complex	RO:0002215	AMPA glutamate receptor activity (GO:0004971)
AMPA glutamate receptor complex	is_a	ionotropic glutamate receptor complex (GO:0008328)

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