Term Information

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Accession
GO:0032281
Name
AMPA glutamate receptor complex
Ontology
cellular_component
Synonyms
AMPA-selective glutamate receptor complex, alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex, AMPA receptor
Alternate IDs
None
Definition
An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus. Source: GOC:ef
Comment
None
History
See term history for GO:0032281 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Parents of AMPA glutamate receptor complex (GO:0032281)
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AMPA glutamate receptor complex [is_a relation] is_a  ionotropic glutamate receptor complex (GO:0008328)
AMPA glutamate receptor complex [RO:0002215 relation] RO:0002215  AMPA glutamate receptor activity (GO:0004971)

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