AmiGO 2: Term Details for "RNA polymerase II, core complex" (GO:0005665)

Notice

Some functionality on this page depends on JavaScript. To fully use the features of AmiGO 2, enable JavaScript in your browser and reload from the landing page.

Term Information

Accession: GO:0005665
Name: RNA polymerase II, core complex
Ontology: cellular_component
Synonyms: DNA-directed RNA polymerase II, core complex, RNA polymerase II complex, RNAP II complex
Alternate IDs: None
Definition: RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template. Source: GOC:krc, GOC:mtg_sensu
Comment: None
History: See term history for GO:0005665 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to RNA polymerase II, core complex (excluding "regulates").; Link to all direct and indirect annotations to RNA polymerase II, core complex (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for RNA polymerase II, core complex (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

GO:0008150 biological_process
GO:0009987 cellular process
GO:0008152 metabolic process
UBERON:0000061 anatomical structure
CARO:0030000 biological entity
GO:0003824 catalytic activity
GO:0003674 molecular_function
GO:0044238 primary metabolic process
CARO:0000000 anatomical entity
GO:0009058 biosynthetic process
GO:0140640 catalytic activity, acting on a nucleic acid
CL:0000000 cell
GO:0110165 cellular anatomical structure
GO:0043170 macromolecule metabolic process
GO:0006139 nucleobase-containing compound metabolic process
GO:0032991 protein-containing complex
GO:0016772 transferase activity, transferring phosphorus-containing groups
UBERON:0001062 anatomical entity
GO:0140098 catalytic activity, acting on RNA
GO:1902494 catalytic complex
GO:0005622 intracellular anatomical structure
GO:0009059 macromolecule biosynthetic process
CARO:0000006 material anatomical entity
GO:0031974 membrane-enclosed lumen
GO:0090304 nucleic acid metabolic process
GO:0034654 nucleobase-containing compound biosynthetic process
GO:0016779 nucleotidyltransferase activity
GO:0043226 organelle
GO:0016740 transferase activity
CARO:0000003 connected anatomical structure
GO:0043229 intracellular organelle
UBERON:0000465 material anatomical entity
GO:0043227 membrane-bounded organelle
GO:0141187 nucleic acid biosynthetic process
GO:0043233 organelle lumen
GO:0016070 RNA metabolic process
GO:0097747 RNA polymerase activity
GO:1990234 transferase complex
GO:0034062 5'-3' RNA polymerase activity
GO:0005575 cellular_component
GO:0043231 intracellular membrane-bounded organelle
GO:0070013 intracellular organelle lumen
GO:0140535 intracellular protein-containing complex
GO:0005634 nucleus
GO:0032774 RNA biosynthetic process
GO:0061695 transferase complex, transferring phosphorus-containing groups
GO:0003899 DNA-directed RNA polymerase activity
GO:0031981 nuclear lumen
GO:0030880 RNA polymerase complex
GO:0000428 DNA-directed RNA polymerase complex
GO:0055029 nuclear DNA-directed RNA polymerase complex
GO:0140513 nuclear protein-containing complex
GO:0005654 nucleoplasm
GO:0016591 RNA polymerase II, holoenzyme
GO:0005665 RNA polymerase II, core complex

Parents of RNA polymerase II, core complex (GO:0005665)

subject	relation	object
RNA polymerase II, core complex	BFO:0000050	RNA polymerase II, holoenzyme (GO:0016591)
RNA polymerase II, core complex	is_a	nuclear DNA-directed RNA polymerase complex (GO:0055029)
RNA polymerase II, core complex	RO:0002162	Eukaryota (NCBITaxon:2759)

This term has no children.

GONUTS Add usage comments for this term on the GONUTS wiki.