AmiGO 2: Term Details for "extracellularly ATP-gated monoatomic cation channel activity" (GO:0004931)

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Term Information

Accession: GO:0004931
Name: extracellularly ATP-gated monoatomic cation channel activity
Ontology: molecular_function
Synonyms: P2X receptor, extracellularly ATP-gated cation channel activity, purinoceptor, purinoreceptor
Alternate IDs: None
Definition: Enables the transmembrane transfer of a monoatomic cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. Source: GOC:bf, PMID:9755289, GOC:mah
Comment: Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'.
History: See term history for GO:0004931 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to extracellularly ATP-gated monoatomic cation channel activity (excluding "regulates").; Link to all direct and indirect annotations to extracellularly ATP-gated monoatomic cation channel activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for extracellularly ATP-gated monoatomic cation channel activity (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

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CARO:0030000 biological entity
GO:0008150 biological_process
CARO:0000000 anatomical entity
GO:0007154 cell communication
GO:0051179 localization
GO:0023052 signaling
UBERON:0001062 anatomical entity
GO:0065007 biological regulation
GO:0007267 cell-cell signaling
GO:0051234 establishment of localization
CARO:0000006 material anatomical entity
GO:0045202 synapse
GO:0110165 cellular anatomical structure
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
GO:0003674 molecular_function
GO:0050789 regulation of biological process
GO:0050896 response to stimulus
GO:0099536 synaptic signaling
GO:0006810 transport
UBERON:0000061 anatomical structure
GO:0030054 cell junction
GO:0051716 cellular response to stimulus
GO:0005575 cellular_component
GO:0006811 monoatomic ion transport
GO:0032501 multicellular organismal process
GO:0050794 regulation of cellular process
GO:0099537 trans-synaptic signaling
GO:0055085 transmembrane transport
GO:0022857 transmembrane transporter activity
GO:0005215 transporter activity
GO:0098916 anterograde trans-synaptic signaling
CL:0000000 cell
GO:0006812 monoatomic cation transport
GO:0034220 monoatomic ion transmembrane transport
GO:0022803 passive transmembrane transporter activity
GO:0065008 regulation of biological quality
GO:0007165 signal transduction
GO:0003008 system process
GO:0007166 cell surface receptor signaling pathway
GO:0015267 channel activity
GO:0007268 chemical synaptic transmission
GO:0098655 monoatomic cation transmembrane transport
GO:0015075 monoatomic ion transmembrane transporter activity
GO:0050877 nervous system process
GO:0098794 postsynapse
GO:0042391 regulation of membrane potential
GO:0099565 chemical synaptic transmission, postsynaptic
GO:0022836 gated channel activity
GO:0022834 ligand-gated channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0008324 monoatomic cation transmembrane transporter activity
GO:0005216 monoatomic ion channel activity
GO:0060078 regulation of postsynaptic membrane potential
GO:0060079 excitatory postsynaptic potential
GO:0005230 extracellular ligand-gated monoatomic ion channel activity
GO:0005261 monoatomic cation channel activity
GO:0035381 ATP-gated ion channel activity
GO:0005231 excitatory extracellular ligand-gated monoatomic ion channel activity
GO:0099094 ligand-gated monoatomic cation channel activity
GO:0004931 extracellularly ATP-gated monoatomic cation channel activity

Parents of extracellularly ATP-gated monoatomic cation channel activity (GO:0004931)

subject	relation	object
extracellularly ATP-gated monoatomic cation channel activity	is_a	ligand-gated monoatomic cation channel activity (GO:0099094)
extracellularly ATP-gated monoatomic cation channel activity	is_a	excitatory extracellular ligand-gated monoatomic ion channel activity (GO:0005231)
extracellularly ATP-gated monoatomic cation channel activity	is_a	ATP-gated ion channel activity (GO:0035381)
extracellularly ATP-gated monoatomic cation channel activity	RO:0002162	Metazoa (NCBITaxon:33208)

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Reactome: R-HSA-877187