Term Information

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Accession
GO:0004931
Name
extracellularly ATP-gated monoatomic cation channel activity
Ontology
molecular_function
Synonyms
P2X receptor, extracellularly ATP-gated cation channel activity, purinoceptor, purinoreceptor
Alternate IDs
None
Definition
Enables the transmembrane transfer of a monoatomic cation by a channel that opens when ATP is bound by the channel complex or one of its constituent parts on the extracellular side of the plasma membrane. Source: GOC:bf, PMID:9755289, GOC:mah
Comment
Note that this term refers to an activity and not a gene product. Consider also annotating to the molecular function term 'purinergic nucleotide receptor activity ; GO:0001614'.
History
See term history for GO:0004931 at QuickGO
Chem. react.
None
Subset
None
Include "regulates"
For more information, please see the ontology relation documentation.

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Graph of GO:0004931 from QuickGO

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Parents of extracellularly ATP-gated monoatomic cation channel activity (GO:0004931)
subject[Reorder by subject] relation[Reorder by relation] object[Reorder by object]
extracellularly ATP-gated monoatomic cation channel activity [is_a relation] is_a  ligand-gated monoatomic cation channel activity (GO:0099094)
extracellularly ATP-gated monoatomic cation channel activity [is_a relation] is_a  ATP-gated ion channel activity (GO:0035381)
extracellularly ATP-gated monoatomic cation channel activity [is_a relation] is_a  excitatory extracellular ligand-gated monoatomic ion channel activity (GO:0005231)

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R-HSA-877187