AmiGO 2: Term Details for "calcium-dependent cysteine-type endopeptidase activity" (GO:0004198)

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Term Information

Accession: GO:0004198
Name: calcium-dependent cysteine-type endopeptidase activity
Ontology: molecular_function
Synonyms: calpain activity
Alternate IDs: None
Definition: Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium. Source: GOC:mah
Comment: None
History: See term history for GO:0004198 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to calcium-dependent cysteine-type endopeptidase activity (excluding "regulates").; Link to all direct and indirect annotations to calcium-dependent cysteine-type endopeptidase activity (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for calcium-dependent cysteine-type endopeptidase activity (excluding "regulates").

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For more information, please see the ontology relation documentation.

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Additional internal viewing options

GO:0003674 molecular_function
GO:0003824 catalytic activity
GO:0140096 catalytic activity, acting on a protein
GO:0016787 hydrolase activity
GO:0008233 peptidase activity
GO:0008234 cysteine-type peptidase activity
GO:0004175 endopeptidase activity
GO:0004197 cysteine-type endopeptidase activity
GO:0004198 calcium-dependent cysteine-type endopeptidase activity
GO:0110158 calpain complex

Parents of calcium-dependent cysteine-type endopeptidase activity (GO:0004198)

subject	relation	object
calcium-dependent cysteine-type endopeptidase activity	is_a	cysteine-type endopeptidase activity (GO:0004197)

Children of calcium-dependent cysteine-type endopeptidase activity (GO:0004198)

subject	relation	object
calpain complex (GO:0110158)	RO:0002215	calcium-dependent cysteine-type endopeptidase activity

EC: 3.4.22.53; 3.4.22.52; 3.4.22.54
Reactome: R-HSA-8848658; R-HSA-8863012; R-HSA-9861485; R-HSA-9855106