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Moody Project Survival Analysis Morris Water Maze Dataset



DOI:10.34945/F51591


DATASET CITATION

Andersen, C.R., Wolf, J.T., Jennings, K., Prough, D.S., Hawkins, B.E. (2020) Moody Project Survival Analysis Morris Water Maze Dataset. ODC-TBI:408. http://doi.org/10.34945/F51591


ABSTRACT

STUDY PURPOSE:to characterize the behavioral consequences of our injury model on Morris Water Maze (MWM) latency with high power from combining animals from 3 studies.

DATA COLLECTED:46 untreated sham and 61 untreated injured male Sprague-Dawley rats, fluid percussion injury model, learning and memory assessed by spatial hidden platform (3 days of 4 swims per rat per day) Morris water maze; outcome measures analyzed included latency recorded in seconds and number of platforms found.

PRIMARY CONCLUSION:We suggest the Accelerated Failure Time (AFT) models should be the preferred analytical methodology for latency to platform associated with MWM studies.


KEYWORDS

Traumatic Brain Injury, Morris Water Maze, Statistics, Survival Analysis, Latency


PROVENANCE / ORIGINATING PUBLICATIONS

  • Mr. Clark R Andersen, Dr. Jordan Wolf, Dr. Kristofer Jennings, Dr. Donald S. Prough, and Dr. Bridget E Hawkins.Journal of Neurotrauma. ahead of print http://doi.org/10.1089/neu.2020.7089

DATASET INFO

Contact:


Lab: Moody Project Consortium


ODC-TBI Accession: 408

Records in Dataset: 1281


Fields per Record: 15


Last updated: 2021-01-05

Date published: 2021-01-05

Downloads: 32


Files: 2


LICENSE

Creative Commons Attribution License (CC-BY 4.0)


FUNDING AND ACKNOWLEDGEMENTS

Darrell K Royal Research Fund for Alzheimer's Disease (BEH), Mission Connect, a Program of TIRR (BEH), The Moody Project for Translational TBI Research (DSP & DSD) and NIH BD2K TCC Data Science RoAD-Trip Fellowship (BEH).


CONTRIBUTORS

Andersen, Clark R. [ORCID:0000-0003-1846-9117]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Wolf, Jordan T [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Jennings, Kristopher [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Prough, Donald S. [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Parsley, Margaret A. [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Hawkins, Bridget E. [ORCID:0000-0002-1887-3657]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Bolding, Ian J. [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Johnson, Kathia M. [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Hausser, Nicole [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Gorman, Sean [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Yamamoto, Satoshi [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
DeWitt, Douglas S. [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555
Prough, Donald S. [ORCID:]
The Moody Project for Translational Traumatic Brain Injury Research, Anesthesiology Department, University of Texas Medical Branch, Galveston, Texas 77555