GenDR Dietary Restriction Gene Manipulation: CDC25
Gene Information (Entrez Gene ID: 851019)
- Symbol
- CDC25
- Aliases
- CTN1
- Name
- Cell Division Cycle 25
- Organism
- Saccharomyces cerevisiae (AnAge)
- Entrez Gene ID
- 851019
Potential relevance to dietary restriction and ageing
- Observations
-
The CDC25-10 allele extends mean and maximum replicative lifespan by 34% and 18%, respectively, at 30 degree Celsius. cdc25-10 mutants have an extended replicative lifespan under ad libitum. Growth on 0.5% glucose restriction does not further extend replicative lifespan of cdc25-10 mutants. CDC25 null mutant is not viable. CDC25 appears to act in the same genetic pathway as SIR2 and NPT1 and is suggested to be a genetic model of DR [2260].
- References
-
In other databases
- GenAge model organism genes
- This gene is present as CDC25
- LongevityMap
- A homolog of this gene for Homo sapiens is present as SOS1
Homologs
- Caenorhabditis elegans
- Y34B4A.4
- Caenorhabditis elegans
- sos-1
- Caenorhabditis elegans
- rgl-1
- Danio rerio
- rgl3a
- Danio rerio
- sos2
- Danio rerio
- 799483
- Danio rerio
- rasgrf2b
- Danio rerio
- RASGRF2 (1 of many)
- Danio rerio
- ralgps1
- Danio rerio
- RASGRF1
- Danio rerio
- rapgef1a
- Danio rerio
- rapgef1b
- Danio rerio
- rgl1
- Danio rerio
- RGL3 (1 of many)
- Danio rerio
- rgl2
- Danio rerio
- ralgps2
- Danio rerio
- sos1
- Danio rerio
- FO834898.1
- Drosophila melanogaster
- Rgl
- Drosophila melanogaster
- CG5522
- Drosophila melanogaster
- C3G
- Drosophila melanogaster
- Sos
- Homo sapiens
- RGL4
- Homo sapiens
- RALGPS2
- Homo sapiens
- SOS1
- Homo sapiens
- RASGRF2
- Homo sapiens
- SOS2
- Homo sapiens
- RGL3
- Homo sapiens
- RALGPS1
- Homo sapiens
- RASGRF1
- Homo sapiens
- RGL1
- Homo sapiens
- RAPGEF1
- Homo sapiens
- RGL2
- Homo sapiens
- RALGDS
- Mus musculus
- Rasgrf2
- Mus musculus
- Rasgrf1
- Mus musculus
- Rgl1
- Mus musculus
- Rapgef1
- Mus musculus
- Ralgps2
- Mus musculus
- Rgl3
- Mus musculus
- Ralgds
- Mus musculus
- Sos2
- Mus musculus
- Rgl2
- Mus musculus
- Sos1
- Mus musculus
- Ralgps1
- Rattus norvegicus
- Ralgps1
- Rattus norvegicus
- Sos2
- Rattus norvegicus
- AABR07007642.1
- Rattus norvegicus
- Rapgef1
- Rattus norvegicus
- Ralgds
- Rattus norvegicus
- Rasgrf1
- Rattus norvegicus
- Rgl1
- Rattus norvegicus
- Ralgps2
- Rattus norvegicus
- Rgl3
- Rattus norvegicus
- Rgl2
- Rattus norvegicus
- Sos1
External links
- Saccharomyces Genome Database
- Search
- Ensembl
- Search
- Entrez Gene
- ID 851019
- Homologues
- Search HomoloGene
- UniProt
- Search
- Internet
- Search Google or Search Google Scholar