appears_in: []
depends_on: []
deprecated: false
description: SPIKE (Signaling Pathways Integrated Knowledge Engine) is a repository
  that can store, organise and allow retrieval of pathway information in a way that
  will be useful for the research community. The database currently focuses primarily
  on pathways describing DNA damage response, cell cycle, programmed cell death and
  hearing related pathways. Pathways are regularly updated, and additional pathways
  are gradually added. The complete database and the individual maps are freely exportable
  in several formats. This collection references pathway maps.
example: spike00001
homepage: http://www.cs.tau.ac.il/~spike/
keywords:
- dna
- gene expression
- pathway
mappings:
  biocontext: SPIKE.MAP
  miriam: spike.map
  n2t: spike.map
  prefixcommons: spike
name: SPIKE Map
namespace_in_lui: false
pattern: ^spike\d{5}$
preferred_prefix: spike.map
prefix: spike.map
providers:
- code: bio2rdf
  description: Bio2RDF is an open-source project that uses Semantic Web technologies
    to build and provide the largest network of Linked Data for the Life Sciences.
    Bio2RDF defines a set of simple conventions to create RDF(S) compatible Linked
    Data from a diverse set of heterogeneously formatted sources obtained from multiple
    data providers.
  homepage: https://bio2rdf.org
  name: Bio2RDF
  uri_format: http://bio2rdf.org/spike:$1
publications:
- doi: 10.1093/nar/gkq1167
  pmc: PMC3014840
  pubmed: '21097778'
  title: 'SPIKE: a database of highly curated human signaling pathways'
  year: 2010
- doi: 10.1186/1471-2105-9-110
  pmc: PMC2263022
  pubmed: '18289391'
  title: SPIKE--a database, visualization and analysis tool of cellular signaling
    pathways
  year: 2008
synonyms: []
uri_format: http://www.cs.tau.ac.il/~spike/maps/$1.html
